Gene Symbol | CLDN18 |
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Entrez Gene | 51208 |
Alt Symbol | SFTA5, SFTPJ |
Species | Human |
Gene Type | protein-coding |
Description | claudin 18 |
Other Description | claudin-18|surfactant associated 5|surfactant associated protein J|surfactant, pulmonary associated protein J |
Swissprots | P56856 A5PL21 Q96PH4 |
Accessions | BAF98890 EAW79092 EAW79093 EAW79094 P56856 AF221069 AAF26448 AF349452 AAL15637 AK098474 AK298103 BAG60388 AY102073 AY358479 AAQ88843 BC063845 BC142708 AAI42709 BC146668 AAI46669 BM785703 NM_001002026 NP_001002026 NM_016369 NP_057453 |
Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}. |
Subcellular Location | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Concentrated at the cell-cell borders of epithelial cells. |
Top Pathways | Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C |
claudin-18 CRISPR/Cas9 KO Plasmid (h) - sc-404431 from Santa Cruz Biotechnology
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claudin-18 HDR Plasmid (h) - sc-404431-HDR from Santa Cruz Biotechnology
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claudin-18 Double Nickase Plasmid (h) - sc-404431-NIC from Santa Cruz Biotechnology
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claudin-18 Double Nickase Plasmid (h2) - sc-404431-NIC-2 from Santa Cruz Biotechnology
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claudin-18 CRISPR Activation Plasmid (h) - sc-404431-ACT from Santa Cruz Biotechnology
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claudin-18 CRISPR Activation Plasmid (h2) - sc-404431-ACT-2 from Santa Cruz Biotechnology
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claudin-18 Lentiviral Activation Particles (h) - sc-404431-LAC from Santa Cruz Biotechnology
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claudin-18 Lentiviral Activation Particles (h2) - sc-404431-LAC-2 from Santa Cruz Biotechnology
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claudin-18 siRNA (h) - sc-105208 from Santa Cruz Biotechnology
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claudin-18 shRNA Plasmid (h) - sc-105208-SH from Santa Cruz Biotechnology
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claudin-18 shRNA (h) Lentiviral Particles - sc-105208-V from Santa Cruz Biotechnology
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Claudin-18 RNAi - H00051208-R01 from Novus Biologicals
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Claudin-18 RNAi - H00051208-R02 from Novus Biologicals
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MISSION® esiRNA - EHU072421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6179 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6179 from Sigma-Aldrich
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CLDN18 siRNA (Human) - CRH9610 from Cohesion Biosciences
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CLDN18 - MBS8201180 from MyBioSource
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shRNA set against Human CLDN18 (NM_016369.3) - SHH264717 from Creative biogene
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shRNA set against Human CLDN18(NM_001002026.2) - SHG180421 from Creative biogene
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shRNA set against Human CLDN18(NM_016369.3) - SHG180439 from Creative biogene
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CLDN18 shRNA Plasmid (Human) - CHH9610 from Cohesion Biosciences
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CLDN18 miRNA 3'UTR clone - MiUTR1H-02190 from Creative biogene
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CLDN18 miRNA 3'UTR clone - MiUTR1H-02191 from Creative biogene
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