Gene Symbol | CLDN18 |
---|---|
Entrez Gene | 51208 |
Alt Symbol | SFTA5, SFTPJ |
Species | Human |
Gene Type | protein-coding |
Description | claudin 18 |
Other Description | claudin-18|surfactant associated 5|surfactant associated protein J|surfactant, pulmonary associated protein J |
Swissprots | P56856 A5PL21 Q96PH4 |
Accessions | BAF98890 EAW79092 EAW79093 EAW79094 P56856 AF221069 AAF26448 AF349452 AAL15637 AK098474 AK298103 BAG60388 AY102073 AY358479 AAQ88843 BC063845 BC142708 AAI42709 BC146668 AAI46669 BM785703 NM_001002026 NP_001002026 NM_016369 NP_057453 |
Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}. |
Subcellular Location | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Concentrated at the cell-cell borders of epithelial cells. |
Top Pathways | Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C |