RFX6

Gene Symbol RFX6
Entrez Gene 222546
Alt Symbol MTCHRS, MTFS, RFXDC1, dJ955L16.1
Species Human
Gene Type protein-coding
Description regulatory factor X, 6
Other Description DNA-binding protein RFX6|regulatory factor X domain-containing protein 1
Swissprots Q5T6B3 Q8HWS3
Accessions EAW48212 EAW48213 Q8HWS3 BC039248 AAH39248 BQ269808 CA842450 CA947154 XM_011535589 XP_011533891 NM_173560 NP_775831
Function Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes. {ECO:0000269|PubMed:20148032}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00858}.
Tissue Specificity Specifically expressed in pancreas, small intestine and colon. {ECO:0000269|PubMed:20148032}.

RFX6 (A-16) - sc-169143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RFX6 (S-15) - sc-169145 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RFXDC1 antibody - ab103497 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RFXDC1 antibody (ab103497) at 1/500 dilution + Human kidney lysate at 50 µg

Anti-RFX6 Antibody (aa181-230) - LS-C205658 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RFX6 antibody Western Blot of Mouse Liver. Antibody dilution: 1 ug/ml.

RFX6 Antibody (811704) - MAB7780 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 811704
Western blot shows lysates of human liver tissue and HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human RFX6 Monoclonal Antibody (Catalog # MAB7780) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for RFX6 at approximately 105 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

RFX6 Antibody - AF7780 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
RFX6 was detected in immersion fixed paraffin-embedded sections of human pancreas using Sheep Anti-Human RFX6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7780) at 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm of islet cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

RFX6 Antibody - NBP2-20143 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RFX6 Antibody [NBP2-20143] - Sample (30 ug of whole cell lysate) A: A549 B: NT2D1 7. 5% SDS PAGE gel, diluted at 1:500.

RFX6 Antibody - H00222546-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RFX6 Antibody [H00222546-D01P] - Analysis of RFX6 expression in human kidney.

RFX6 Antibody - H00222546-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: RFX6 Antibody [H00222546-B01P] - Analysis of RFX6 expression in transfected 293T cell line by RFX6 polyclonal antibody. Lane 1: RFXDC1 transfected lysate(102.08 KDa). Lane 2: Non-transfected lysate.

RFX6 Antibody - H00222546-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RFX6 antibody produced in rabbit - HPA037696 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RFX6: <B>Cat. No. HPA037696</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islets of Langerhans.

Anti-RFXDC1 antibody produced in mouse - SAB1408444 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RFXDC1: <B>Cat. No. SAB1408444</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~102.1 kDa using RFX6 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-RFX6 antibody produced in rabbit - SAB1402062 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-RFX6, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1402062</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~102.46 kDa using human kidney lysate.

Human RFX6 Antibody - MAB7780 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 811704
Detection of Human RFX6 by Western Blot. Western blot shows lysates of human liver tissue and HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human RFX6 Monoclonal Antibody (Catalog # MAB7780) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018 ). A specific band was detected for RFX6 at approximately 105 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .

Human RFX6 MAb (Clone 811704), Mouse IgG2B - MAB7780-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 811704
Detection of Human RFX6 by Western Blot. Western blot shows lysates of human liver tissue and HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human RFX6 Monoclonal Antibody (Catalog # MAB7780) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for RFX6 at approximately 105 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Human RFX6 Antibody - AF7780 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
RFX6 in Human Pancreas. RFX6 was detected in immersion fixed paraffin-embedded sections of human pancreas using Sheep Anti-Human RFX6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7780) at 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019 ) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm of islet cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections .

Human RFX6 Affinity Purified Polyclonal Ab, Sheep IgG - AF7780-SP from R&D Systems

Host Sheep
Clonality Polyclonal
RFX6 in Human Pancreas. RFX6 was detected in immersion fixed paraffin-embedded sections of human pancreas using Sheep Anti-Human RFX6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7780) at 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm of islet cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

RFX6 antibody - H00222546-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of RFX6 expression in transfected 293T cell line (H00222546-T01) by RFX6 MaxPab polyclonal antibody.Lane 1: RFXDC1 tran

RFX6 antibody - H00222546-D01 from Acris Antibodies

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RFX6 antibody - H00222546-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
RFX6 MaxPab rabbit polyclonal antibody. Western Blot analysis of RFX6 expression in human kidney.

Anti-RFX6 monoclonal antibody - DCABH-13235 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

RFX6 Polyclonal Antibody - PA5-28878 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of RFX6 in paraffin-embedded colon carcinoma using a RFX6 polyclonal antibody (Product # PA5-28878) at a dilution of 1:500.

RFX6 - MBS270182 from MyBioSource

Prices $360.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Colon ca, using RFX6 antibody at 1:500 dilution.

PCRP-RFX6-1B12 - PCRP-RFX6-1B12 from Developmental Studies Hybridoma Bank

Host Mouse
Clonality Monoclonal

PCRP-RFX6-3D3 - PCRP-RFX6-3D3 from Developmental Studies Hybridoma Bank

Host Mouse
Clonality Monoclonal
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