ENAH

Gene Symbol	ENAH
Entrez Gene	55740
Alt Symbol	ENA, MENA, NDPP1
Species	Human
Gene Type	protein-coding
Description	enabled homolog (Drosophila)
Other Description	mammalian enabled variant 11a|mammalian enabled variant pan|protein enabled homolog
Swissprots	Q9UFB8 Q502W5 Q8N8S7 Q9NVF3 Q5VTR0 Q5VTQ9 Q5T5M7 D0PQI2
Accessions	CCG13846 EAW69747 Q8N8S7 AF519769 AAQ08487 AK001635 BAA91799 AK025108 AK096246 BAC04736 AK126894 BAC86739 AK127561 BAC87036 AK290179 BAF82868 AL133059 CAB61384 AY345143 AAR04685 BC010414 BC037319 BC065238 AAH65238 BC095481 AAH95481 BQ672102 CB961874 CB991931 EU255274 ABY78022 KM214203 AIU47267 KM214204 AIU47268 XM_005273187 XP_005273244 XM_006711795 XP_006711858 XM_006711796 XP_006711859 XM_006711797 XP_006711860 XM_011544229 XP_011542531 XM_011544230 XP_011542532 XM_011544231 XP_011542533 XM_011544232 XP_011542534 XM_011544233 XP_011542535 XM_011544234 XP_011542536 XM_011544235 XP_011542537 NM_001008493 NP_001008493 NM_018212 NP_060682
Function	Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cell junction, focal adhesion. Note=Targeted to the leading edge of lamellipodia and filopodia by MRL family members. Colocalizes at filopodial tips with a number of other proteins including vinculin and zyxlin. Colocalizes with N-WASP at the leading edge. Colocalizes with GPHN and PFN at synapses (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in myoepithelia of parotid, breast, bronchial glands and sweat glands. Expressed in colon-rectum muscolaris mucosae epithelium, pancreas acinar ductal epithelium, endometrium epithelium, prostate fibromuscolar stroma and placenta vascular media. Overexpressed in a majority of breast cancer cell lines and primary breast tumor lesions. {ECO:0000269|PubMed:15027125}.
Top Pathways	Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ENAH protein fragment - ab163199 from Abcam Category Protein Source Wheat germ Species Human

ENAH / MENA Antibody Blocking Peptide - LS-E6505 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ENAH / MENA Antibody Blocking Peptide - LS-E20845 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Mena Protein - H00055740-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ENAH-Antibody-C-term-Blocking-Peptide - BP19271b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ENA protein - orb107937 from Biorbyt Category Protein Prices $476.00 Sizes 250 µl

ENAH / MENA - H00055740-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ENAH / MENA - H00055740-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ENAH fusion protein - ag18218 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ENAH fusion protein - Ag24200 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Protein enabled homolog(ENAH) - CSB-YP854072HU CSB-EP854072HU CSB-BP854072HU CSB-MP854072HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ENAH / MENA (transcript variant 1) - TP310677 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ENAH / MENA (transcript variant 2) - TP315455 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Mena Recombinant Protein Antigen - NBP1-87915PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Mena Recombinant Protein Antigen - NBP1-87914PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MENA Blocking Peptide - abx061684 from Abbexa Category Peptide

ENAH Peptide, Human - M34GP04925H from Creative Peptides Category Peptide Source Synthetic. Species Human

MENA Blocking Peptide - CBP7074 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse

Ena/VASP-like protein (EVL), Recombinant Protein - MBS1348115 from MyBioSource Category Protein Prices $1,195.00, $1,195.00, $1,415.00, $1,415.00, $1,930.00, $1,930.00, $2,395.00, $2,395.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Orangutan

Protein enabled homolog (ENAH), Recombinant Protein - MBS1358724 from MyBioSource Category Protein Prices $1,390.00, $1,390.00, $1,610.00, $1,610.00, $2,325.00, $2,325.00, $2,770.00, $2,770.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ENAH fusion protein - Ag24267 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Search more