FOXA3

Gene Symbol FOXA3
Entrez Gene 3171
Alt Symbol FKHH3, HNF3G, TCF3G
Species Human
Gene Type protein-coding
Description forkhead box A3
Other Description HNF-3-gamma|HNF-3G|TCF-3G|fork head-related protein FKH H3|forkhead box protein A3|hepatocyte nuclear factor 3, gamma|hepatocyte nuclear factor 3-gamma|transcription factor 3G
Swissprots A9LYI5 P55318 Q53F16 Q9UMW9
Accessions AAD51980 ABX44664 EAW57394 EAW57395 P55318 AK223473 BAD97193 BC016024 AAH16024 BT006720 AAP35366 L12141 AAA58477 NM_004497 NP_004488
Function Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; binds to and activates transcription from the G6PC promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis. {ECO:0000250, ECO:0000269|PubMed:12695546}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089, ECO:0000269|PubMed:19706729}.
Tissue Specificity Expressed in erythroleukemia and hepatoma cell lines and in liver and pancreas. Not expressed in any other cell lines or tissues examined. {ECO:0000269|PubMed:8499623}.
Top Pathways Maturity onset diabetes of the young

HNF-3γ (G-2) - sc-271229 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HNF-3γ (G-2): sc-271229. Western blot analysis of HNF-3γ expression in non-transfected: sc-110760 (A) and human HNF-3γ transfected: sc-111854 (B) 293 whole cell lysates.

HNF-3γ (A-2) - sc-74424 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HNF-3γ (A-2): sc-74424. Western blot analysis of HNF-3γ expression in Hep G2 whole cell lysate (A) and Hep G2 nuclear extract (B).

HNF-3γ (D-4) - sc-166703 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HNF-3γ (D-4): sc-166703. Western blot analysis of HNF-3γ expression in non-transfected: sc-110760 (A) and human HNF-3γ transfected: sc-111854 (B) 293 whole cell lysates.

HNF-3γ (H-115) - sc-25357 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HNF-3γ (H-115): sc-25357. Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear staining of respiratory epithelial cells.

HNF-3γ (K-15) - sc-5360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNF-3γ (K-15): sc-5360. Western blot analysis of HNF-3γ expression in non-transfected: sc-110760 (A) and human HNF-3γ transfected: sc-111854 (B) 293 whole cell lysates.

HNF-3γ (N-14) - sc-34622 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNF-3γ (N-14): sc-34622. Western blot analysis of HNF-3γ expression in non-transfected: sc-110760 (A) and human HNF-3γ transfected: sc-111854 (B) 293 whole cell lysates.

HNF-3γ (N-19) - sc-5361 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNF-3γ (N-19): sc-5361. Western blot analysis of HNF-3γ expression in Hep G2 whole cell lysate (A) and mouse embryo extract (B).

HNF-3γ (T-13) - sc-34625 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNF-3γ (T-13): sc-34625. Western blot analysis of HNF-3γ expression in non-transfected: sc-110760 (A) and human HNF-3γ transfected: sc-111854 (B) 293 whole cell lysates.

HNF-3γ (P-13) - sc-34623 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNF-3γ (P-13): sc-34623. Western blot analysis of HNF-3γ expression in non-transfected: sc-110760 (A) and human HNF-3γ transfected: sc-111854 (B) 293 whole cell lysates.

HNF-3γ (V-17) - sc-5362 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNF-3γ (V-17): sc-5362. Immunofluorescence staining of methanol-fixed Hep G2 cells showing nuclear localization.

Anti-FOXA3 Antibody (clone 1C6) - LS-C197426 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C6
Detection limit for recombinant GST tagged FOXA3 is 0.03 ng/ml as a capture antibody.

Anti-FOXA3 Antibody (aa201-250) IHC-plus™ - LS-B947 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FOXA3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B947 concentration 5 ug/ml.

Anti-FOXA3 Antibody - LS-C6936 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-FOXA3 Antibody (Internal) - LS-C209884 from LifeSpan Bioscience

Prices $405.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXA3 Antibody - LS-C310391 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXA3 Antibody - LS-C307591 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-FOXA3 Antibody (C-Terminus) - LS-C116004 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FOXA3 antibody LS-C116004 Western blot of Mouse Brain lysate.

FOXA3 Antibody - NBP1-74486 from Novus Biologicals

Prices $309.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FOXA3 Antibody [NBP1-74486] - Jurkat cell lysate stained by RbxFOXA3 @ 1:200 (Protein Amount: Lane 1: 20 ug, Lane 2: 10 ug, Lane 3: 5 ug

FOXA3 Antibody (1C6) - H00003171-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C6

FOXA3 Antibody - H00003171-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: FOXA3 Antibody [H00003171-B01P] - Analysis of FOXA3 expression in transfected 293T cell line by FOXA3 polyclonal antibody. Lane 1: FOXA3 transfected lysate(38.5 KDa). Lane 2: Non-transfected lysate.

FOXA3 Antibody - H00003171-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-FOXA3 antibody produced in mouse - SAB1401184 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C6
<B>Immunoblotting</B><BR/>Monoclonal Anti-FOXA3, antibody produced in mouse, clone 1C6, purified immunoglobulin: <B>Cat. No. SAB1401184</B>: Antibody concentration: 1.0 μg/mL. Specific band of ~35.46 kDa using immunogen protein lysate.

Anti-FOXA3 antibody produced in mouse - SAB1405950 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-FOXA3: <B>Cat. No. SAB1405950</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~38.5 kDa using FOXA3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-FOXA3 antibody produced in rabbit - AV31945 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FOXA3: <B>Cat. No. AV31945</B>: Immunohistochemistry of FOXA3 in Human Lung tissue with FOXA3 antibody at 4-8 μg/mL.

FOXA3 antibody - middle region (ARP31945_P050) - ARP31945_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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