Gene Symbol | RNASE7 |
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Entrez Gene | 84659 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ribonuclease, RNase A family, 7 |
Other Description | RNase 7|SAP-2|ribonuclease 7|skin-derived antimicrobial protein 2 |
Swissprots | Q546N3 Q9H1E1 P80927 P83685 |
Accessions | EAW66418 EAW66419 Q9H1E1 AI150610 AJ131212 CAC20410 AJ306608 CAC84462 AJ306609 CAC84457 AJ306610 CAC84458 AK292697 BAF85386 AY170392 AAO12510 AY359097 AAQ89455 BC074960 AAH74960 BC112334 AAI12335 DB153740 NM_032572 NP_115961 |
Function | Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. {ECO:0000269|PubMed:12244054, ECO:0000269|PubMed:12527768, ECO:0000269|PubMed:17150966}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart. {ECO:0000269|PubMed:12244054, ECO:0000269|PubMed:12527768}. |
RNase 7 (C-14) - sc-165374 from Santa Cruz Biotechnology
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RNase 7 (S-12) - sc-165375 from Santa Cruz Biotechnology
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Anti-Ribonuclease 7 antibody - ab81470 from Abcam
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Anti-Ribonuclease 7 antibody [3C2] - ab189222 from Abcam
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Anti-Ribonuclease 7 antibody [CL0224] - ab154143 from Abcam
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Anti-RNASE7 Antibody (N-Terminus) - LS-C145009 from LifeSpan Bioscience
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Anti-RNASE7 Antibody (aa31-155, Biotin) - LS-C300880 from LifeSpan Bioscience
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Anti-RNASE7 Antibody (aa31-155, FITC) - LS-C304476 from LifeSpan Bioscience
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Anti-RNASE7 Antibody (aa31-155) - LS-C296273 from LifeSpan Bioscience
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RNASE7 Antibody - NBP1-86134 from Novus Biologicals
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RNASE7 Antibody - NBP1-21311 from Novus Biologicals
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Monoclonal Anti-RNASE7 antibody produced in mouse - AMAB90583 from Sigma-Aldrich
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Monoclonal Anti-RNASE7 antibody produced in mouse - AMAB90582 from Sigma-Aldrich
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Anti-RNASE7 antibody produced in rabbit - HPA005690 from Sigma-Aldrich
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RNASE7 antibody - AM33434PU-N from Acris Antibodies
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RNASE7 antibody - AM33435PU-N from Acris Antibodies
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RNASE7 antibody - AM33436PU-N from Acris Antibodies
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RNASE7 antibody - AP55252SU-N from Acris Antibodies
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Anti-Ribonuclease A7 (RNASE7) - 20-4803 from ARP American Research Products
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RNASE7 antibody - 18014-1-AP from Proteintech Group
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Monoclonal Antibody to Ribonuclease A7 (RNASE7) - MAD193Hu21 from Uscn Life Science Inc.
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Polyclonal Antibody to Ribonuclease A7 (RNASE7) - PAD193Hu01 from Uscn Life Science Inc.
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Biotin-Linked Antibody to Ribonuclease A7 (RNASE7) - PAD193Hu71 from Uscn Life Science Inc.
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Anti-RNASE7 monoclonal antibody - DCABH-13265 from Creative Diagnostics
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Anti-RNASE7 monoclonal antibody, clone DM1335 - DCABH-4295 from Creative Diagnostics
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