Gene Symbol | ASPA |
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Entrez Gene | 443 |
Alt Symbol | ACY2, ASP |
Species | Human |
Gene Type | protein-coding |
Description | aspartoacylase |
Other Description | ACY-2|aminoacylase 2|aminoacylase-2 |
Swissprots | P45381 |
Accessions | AAD14981 EAW90506 EAW90507 P45381 AK312901 BAG35747 BC010941 BC029128 AAH29128 CR541908 CAG46706 DQ892079 ABM83005 DQ895272 ABM86198 S67156 AAB29190 XM_006721527 XP_006721590 XR_934026 NM_000049 NP_000040 NM_001128085 NP_001121557 |
Function | Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids. |
Subcellular Location | Cytoplasm. Nucleus {ECO:0000250}. |
Tissue Specificity | Brain white matter, skeletal muscle, kidney, adrenal glands, lung and liver. |
Top Pathways | Alanine, aspartate and glutamate metabolism, Histidine metabolism |
ASPA-Over-expression-Lysate - LY10803a from Abgent, a WuXi AppTec company
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Aminoacylase-2 / ACY2 Lysate(Denatured) - H00000443-T01 from Acris Antibodies
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ASPA 293 Cell Lysate - 410338 from ABBIOTEC
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ASPA Overexpression Lysate (Denatured) - H00000443-T01 from Novus Biologicals
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ASPA Overexpression Lysate (Native) - NBL1-07772 from Novus Biologicals
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Aspartoacylase (h): 293T Lysate - sc-170145 from Santa Cruz Biotechnology
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Aspartoacylase (h): 293T Lysate - sc-114276 from Santa Cruz Biotechnology
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ASPA Over-expression Lysate Product - GWB-CD48E8 from Genway Biotech
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ASPA Overexpression Lysate (Native) - NBP2-09465 from Novus Biologicals
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Panoply™ Human ASPA Knockdown Stable Cell Line - CSC-DC001052 from Creative biogene
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