Gene Symbol | ASPA |
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Entrez Gene | 443 |
Alt Symbol | ACY2, ASP |
Species | Human |
Gene Type | protein-coding |
Description | aspartoacylase |
Other Description | ACY-2|aminoacylase 2|aminoacylase-2 |
Swissprots | P45381 |
Accessions | AAD14981 EAW90506 EAW90507 P45381 AK312901 BAG35747 BC010941 BC029128 AAH29128 CR541908 CAG46706 DQ892079 ABM83005 DQ895272 ABM86198 S67156 AAB29190 XM_006721527 XP_006721590 XR_934026 NM_000049 NP_000040 NM_001128085 NP_001121557 |
Function | Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids. |
Subcellular Location | Cytoplasm. Nucleus {ECO:0000250}. |
Tissue Specificity | Brain white matter, skeletal muscle, kidney, adrenal glands, lung and liver. |
Top Pathways | Alanine, aspartate and glutamate metabolism, Histidine metabolism |
Aspartoacylase (F-1) - sc-365588 from Santa Cruz Biotechnology
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Aspartoacylase (D-12) - sc-109208 from Santa Cruz Biotechnology
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Aspartoacylase (D-11) - sc-377308 from Santa Cruz Biotechnology
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Aspartoacylase (H-93) - sc-98734 from Santa Cruz Biotechnology
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Aspartoacylase (N-13) - sc-109212 from Santa Cruz Biotechnology
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Aspartoacylase (E-16) - sc-109209 from Santa Cruz Biotechnology
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Anti-ASPA antibody - ab154503 from Abcam
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Anti-ASPA antibody - ab54849 from Abcam
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Anti-ASPA Antibody (aa77-313, clone 3G7) - LS-C339540 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa77-313, clone 5B8) - LS-C339506 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa77-313, clone 5C7) - LS-C339554 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa77-313, clone 1A11) - LS-C339553 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa77-313, clone 4H4) - LS-C339555 from LifeSpan Bioscience
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Anti-ASPA Antibody (C-Terminus) - LS-C139740 from LifeSpan Bioscience
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Anti-ASPA Antibody - LS-C346318 from LifeSpan Bioscience
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Anti-ASPA Antibody (clone 3C11) - LS-C196702 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa77-313, clone 2D2) - LS-C339556 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa39-300) IHC-plus™ - LS-B10894 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa89-118) - LS-C156546 from LifeSpan Bioscience
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Anti-ASPA Antibody - LS-C306408 from LifeSpan Bioscience
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Anti-ASPA Antibody - LS-C309528 from LifeSpan Bioscience
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Anti-ASPA Antibody - LS-C309529 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa143-192) - LS-C111790 from LifeSpan Bioscience
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Anti-ASPA Antibody (aa71-120) - LS-C111789 from LifeSpan Bioscience
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ASPA Antibody - NBP1-31754 from Novus Biologicals
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