| Gene Symbol | GRPEL2 |
|---|---|
| Entrez Gene | 134266 |
| Alt Symbol | Mt-GrpE#2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | GrpE-like 2, mitochondrial (E. coli) |
| Other Description | grpE protein homolog 2, mitochondrial |
| Swissprots | Q8TAA5 B4DFA6 Q49AJ6 |
| Accessions | EAW61786 Q8TAA5 AK074293 BAB85040 AK091237 AK096445 AK294005 BAG57367 AL704536 AL832325 CAD38619 BC036678 AAH36678 BC070090 AAH70090 HQ447481 ADQ31967 NM_152407 NP_689620 |
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity). {ECO:0000250}. |
| Subcellular Location | Mitochondrion matrix {ECO:0000250}. |
GrpE-like 2, mitochondrial (E. coli) , ELISA Kit - MBS9339071 from MyBioSource
|
||||||
Human GRPEL2 ELISA Kit - E017651 from Biobool
|