GCNT4

Gene Symbol GCNT4
Entrez Gene 51301
Alt Symbol C2GNT3
Species Human
Gene Type protein-coding
Description glucosaminyl (N-acetyl) transferase 4, core 2
Other Description beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4|core 2 beta-1,6-N-acetylglucosaminyltransferase 3|core 2-branching enzyme 3|core2-GlcNAc-transferase 3|glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
Swissprots Q9P109
Accessions CAC34674 CAD35101 EAW95751 Q9P109 AF132035 AAF63156 BC160070 AAI60070 NM_016591 NP_057675
Function Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity. {ECO:0000269|PubMed:10753916}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node. {ECO:0000269|PubMed:10753916}.
Top Pathways Mucin type O-Glycan biosynthesis

GCNT4 CRISPR/Cas9 KO Plasmid (h) - sc-412177 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT4 HDR Plasmid (h) - sc-412177-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT4 Double Nickase Plasmid (h) - sc-412177-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT4 Double Nickase Plasmid (h2) - sc-412177-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT4 CRISPR Activation Plasmid (h) - sc-412177-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT4 CRISPR Activation Plasmid (h2) - sc-412177-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT4 Lentiviral Activation Particles (h) - sc-412177-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT4 Lentiviral Activation Particles (h2) - sc-412177-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT4 siRNA (h) - sc-91629 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GCNT4 shRNA Plasmid (h) - sc-91629-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GCNT4 shRNA (h) Lentiviral Particles - sc-91629-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU000921 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9199 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9199 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GCNT4 siRNA (Human) - CRH9678 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GCNT4 - MBS828857 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GCNT4 (NM_016591.2) - SHH300138 from Creative biogene

Category siRNA
Species Reactivities Human

Human GCNT4 siRNA - orb270180 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GCNT4 shRNA Plasmid (Human) - CHH9678 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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