Gene Symbol | GCNT4 |
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Entrez Gene | 51301 |
Alt Symbol | C2GNT3 |
Species | Human |
Gene Type | protein-coding |
Description | glucosaminyl (N-acetyl) transferase 4, core 2 |
Other Description | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4|core 2 beta-1,6-N-acetylglucosaminyltransferase 3|core 2-branching enzyme 3|core2-GlcNAc-transferase 3|glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase) |
Swissprots | Q9P109 |
Accessions | CAC34674 CAD35101 EAW95751 Q9P109 AF132035 AAF63156 BC160070 AAI60070 NM_016591 NP_057675 |
Function | Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity. {ECO:0000269|PubMed:10753916}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node. {ECO:0000269|PubMed:10753916}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
Anti-C2GNT3 antibody - ab102814 from Abcam
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Anti-C2GNT3 antibody - ab68765 from Abcam
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Anti-C2GNT3 / GCNT4 Antibody - LS-C307660 from LifeSpan Bioscience
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Anti-C2GNT3 / GCNT4 Antibody (aa328-377) - LS-C81022 from LifeSpan Bioscience
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C2GNT3 Antibody - NBP1-69591 from Novus Biologicals
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C2GNT3 Antibody - NBP1-88270 from Novus Biologicals
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C2GNT3 Antibody - H00051301-B01P from Novus Biologicals
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C2GNT3 Polyclonal Antibody - bs-15145R from Bioss
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C2GNT3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15145R-A350 from Bioss
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C2GNT3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15145R-A488 from Bioss
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C2GNT3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15145R-A555 from Bioss
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C2GNT3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15145R-A647 from Bioss
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C2GNT3 Polyclonal Antibody, Cy3 Conjugated - bs-15145R-Cy3 from Bioss
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C2GNT3 Polyclonal Antibody, Cy5 Conjugated - bs-15145R-Cy5 from Bioss
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C2GNT3 Polyclonal Antibody, Cy5.5 Conjugated - bs-15145R-Cy5.5 from Bioss
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C2GNT3 Polyclonal Antibody, Cy7 Conjugated - bs-15145R-Cy7 from Bioss
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C2GNT3 Polyclonal Antibody, FITC Conjugated - bs-15145R-FITC from Bioss
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C2GNT3 Polyclonal Antibody, Biotin Conjugated - bs-15145R-Biotin from Bioss
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C2GNT3 Polyclonal Antibody, HRP Conjugated - bs-15145R-HRP from Bioss
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Anti-GCNT4 antibody produced in rabbit - AV47278 from Sigma-Aldrich
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Anti-GCNT4 antibody produced in rabbit - HPA037431 from Sigma-Aldrich
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Anti-GCNT4 antibody produced in mouse - SAB1407477 from Sigma-Aldrich
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GCNT4 antibody - C-terminal region (ARP47278_P050) - ARP47278_P050 from Aviva Systems Biology
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GCNT4 antibody, C-term - GTX46337 from GeneTex
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Anti -GCNT4 (Beta-1,3-galactosyl-O-glycosyl-glycoproteinbeta-1,6-N-acetylglucosaminyltransferase 4, Core 2-branching Enzyme 3,Core2-GlcNAc-transferase 3, C2GnT3) - 127241 from USBiological Life Science
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