Mapt

Gene Symbol	Mapt
Entrez Gene	17762
Alt Symbol	AI413597, AW045860, Mtapt, Tau
Species	Mouse
Gene Type	protein-coding
Description	microtubule-associated protein tau
Other Description	PHF-tau|neurofibrillary tangle protein|paired helical filament-tau
Swissprots	Q60685 P10637 P10638 Q91WK4 Q60686 A2A5Y9 Q62286 Q60684
Accessions	BAA18878 BAC20951 BAC20952 EDL34210 EDL34211 EDL34212 EDL34213 EDL34214 EDL34215 EDL34216 EDL34217 P10637 AF483518 AAL90792 AF483519 AAL90793 AK038797 AK078167 BAC37157 AK135147 AK147636 BAE28038 BC014748 AAH14748 BI202659 BM950831 BY249380 CA450773 CO432693 M18775 AAA40165 M18776 AAA40166 M93266 U12914 AAA58343 U12915 AAA58344 U12916 AAA58345 W18770 Z12133 CAA78121 XM_006514928 XP_006514991 XM_006514929 XP_006514992 XM_006514930 XP_006514993 XM_006514931 XP_006514994 XM_006532407 XP_006532470 XM_006532408 XP_006532471 XM_006532409 XP_006532472 XM_006532410 XP_006532473 XM_011248785 XP_011247087 XM_011248786 XP_011247088 XM_011248787 XP_011247089 XM_011248788 XP_011247090 XM_011251345 XP_011249647 XM_011251346 XP_011249648 XM_011251347 XP_011249649 XM_011251348 XP_011249650 NM_001038609 NP_001033698 NM_001285454 NP_001272383 NM_001285455 NP_001272384 NM_001285456 NP_001272385 NM_010838 NP_034968
Function	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Subcellular Location	Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
Tissue Specificity	Expressed in neurons and at a lower level in the liver and kidney. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
Top Pathways	Alzheimer's disease, MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse MAPT / Tau ELISA Kit (Sandwich ELISA) - LS-F6386 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Microtubule Associated Protein Tau (MAPt), Mouse, ELISA Kit - SEB983Mu from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity 2.9pg/mL Range 7.8-500pg/mL

Microtubule-associated protein tau, Mapt, Mouse, ELISA Kit - E1983m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Tau Protein, Mouse, ELISA Kit - E03T0024 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Range 0.5-10ng/ml

Tau Proteins, Mouse, ELISA Kit - CSB-E13791m from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Mouse Tau ELISA Kit - MT0031 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

microtubule-associated protein tau, ELISA Kit - MBS702809 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Tau Proteins ELISA kit - CSB-E13791m from Cusabio Category ELISA Kit Sensitivity Request Information Range Request Information

Mouse Tau Protein ELISA - E03T0024 from BlueGene Biotech Category ELISA Kit

ELISA Kit for Microtubule Associated Protein Tau (MAPt) - SEB983Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 2.9pg/mL. Range 7.813-500pg/mL The standard curve concentrations used for the ELISA's were 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL, 7.813pg/mL

Mouse MAPT / Tau ELISA Kit (Custom ELISA) - LS-F18967 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse MAPTau(Microtubule Associated Protein Tau/Tau Protein) ELISA Kit - E-EL-M1121 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 9.38 pg/mL Range 15.63~1000 pg/mL

Mouse MMP-8 (Matrix Metalloproteinase 8) CLIA Kit - E-CL-M0495 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.188ng/mL Range 0.313-20ng/mL

Mouse MAPt ELISA Kit - abx154355 from Abbexa Category ELISA Kit Range 7.81 pg/ml - 500 pg/ml

Mouse Microtubule Associated Protein Tau/Tau Protein ELISA Kit - abx254256 from Abbexa Category ELISA Kit Sensitivity 9.375 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Mouse MAPT / Tau ELISA Kit (Sandwich ELISA) - LS-F23117 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 0.156-10 ng/ml

Microtubule Associated Protein Tau (MAPt), Mouse, ELISA Kit - DL-MAPt-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 7.8-500 pg/mL

Mouse MAPt ELISA Kit - abx576201 from Abbexa Category ELISA Kit Sensitivity 2.9 pg/ml Range 7.813 pg/ml - 500 pg/ml

MAPT ELISA Kit (Mouse) : 96 Wells (OKEH01411) - OKEH01411 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 10 pg/ml Range 15.6 - 1000 pg/mL

Mouse Mapt ELISA Kit - E060115 from Biobool Category ELISA Kit Sensitivity Typically less than 2.9pg/mL.

Mouse TAU ELISA Kit - E069619 from Biobool Category ELISA Kit Sensitivity 2.0 pg/ml.

Mapt High Sensitivity ELISA Kit (Mouse) (OKCD01361) - OKCD01361 from Aviva Systems Biology Category ELISA Kit Prices $575.00 Sizes 96 wells Sensitivity 2.5 pg/mL Range 7.8-500 pg/mL

Mouse Tau ELISA Kit - EMT0031 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse Microtubule-associated protein tau ELISA Kit - EK4154 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Range 0.312-20 ng/mL

Mouse Microtubule-associated protein tau (MAPT) ELISA Kit - AE34248MO from ARP American Research Products Category ELISA Kit Prices $612.00 Sizes 96 t Sensitivity 0.078 ng/mL Range 0.156-10 ng/mL

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