Mapt

Gene Symbol Mapt
Entrez Gene 17762
Alt Symbol AI413597, AW045860, Mtapt, Tau
Species Mouse
Gene Type protein-coding
Description microtubule-associated protein tau
Other Description PHF-tau|neurofibrillary tangle protein|paired helical filament-tau
Swissprots Q60685 P10637 P10638 Q91WK4 Q60686 A2A5Y9 Q62286 Q60684
Accessions BAA18878 BAC20951 BAC20952 EDL34210 EDL34211 EDL34212 EDL34213 EDL34214 EDL34215 EDL34216 EDL34217 P10637 AF483518 AAL90792 AF483519 AAL90793 AK038797 AK078167 BAC37157 AK135147 AK147636 BAE28038 BC014748 AAH14748 BI202659 BM950831 BY249380 CA450773 CO432693 M18775 AAA40165 M18776 AAA40166 M93266 U12914 AAA58343 U12915 AAA58344 U12916 AAA58345 W18770 Z12133 CAA78121 XM_006514928 XP_006514991 XM_006514929 XP_006514992 XM_006514930 XP_006514993 XM_006514931 XP_006514994 XM_006532407 XP_006532470 XM_006532408 XP_006532471 XM_006532409 XP_006532472 XM_006532410 XP_006532473 XM_011248785 XP_011247087 XM_011248786 XP_011247088 XM_011248787 XP_011247089 XM_011248788 XP_011247090 XM_011251345 XP_011249647 XM_011251346 XP_011249648 XM_011251347 XP_011249649 XM_011251348 XP_011249650 NM_001038609 NP_001033698 NM_001285454 NP_001272383 NM_001285455 NP_001272384 NM_001285456 NP_001272385 NM_010838 NP_034968
Function Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Subcellular Location Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
Tissue Specificity Expressed in neurons and at a lower level in the liver and kidney. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
Top Pathways Alzheimer's disease, MAPK signaling pathway

Recombinant Microtubule Associated Protein Tau (MAPt) - RPB983Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Microtubule Associated Protein Tau (MAPt) - RPB983Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Microtubule-associated protein tau(Mapt) - CSB-YP013481MO CSB-EP013481MO CSB-BP013481MO CSB-MP013481MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Mapt Recombinant Protein (OPCA03252) - OPCA03252 from Aviva Systems Biology

Category Protein
Prices $365.00
Sizes 50 µg
Source Mouse

Mouse Mapt protein - orb358485 from Biorbyt

Category Protein
Prices $298.00, $527.00, $995.00, $1,649.00, $2,601.00
Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg
Species Mouse

MAPT Recombinant Protein (OPCD05136) - OPCD05136 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Microtubule-associated protein tau(Mapt) - AP74284 from Signalway Antibody

Category Protein
Prices $155.00, $390.00, $665.00, $1,090.00, $1,835.00, $2,915.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg
Source Yeast
Species Mouse

Microtubule-associated protein tau, Recombinant Protein - MBS964528 from MyBioSource

Category Protein
Prices $135.00, $255.00, $420.00, $665.00, $1,090.00, $1,165.00, $1,310.00, $1,560.00, $1,570.00, $1,660.00, $1,725.00, $1,735.00, $2,345.00, $2,370.00, $2,470.00, $3,100.00
Sizes 10 µg (Yeast), 50 µg (Yeast), 100 µg (Yeast), 200 µg (Yeast), 500 µg (Yeast), 50 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 200 µg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 500 µg (E-Coli), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (E-Coli), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Microtubule-associated protein tau (Mapt), Recombinant Protein - MBS9423864 from MyBioSource

Category Protein
Prices $200.00, $380.00, $610.00, $960.00, $1,570.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg
Source Yeast
Species Mouse
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