Gene Symbol | ZFP57 |
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Entrez Gene | 346171 |
Alt Symbol | C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2 |
Species | Human |
Gene Type | protein-coding |
Description | ZFP57 zinc finger protein |
Other Description | zfp-57|zinc finger protein 57 homolog|zinc finger protein 698 |
Swissprots | B0S894 Q5SSB1 Q9NU63 B0V254 B2RXJ7 |
Accessions | CAB89275 Q9NU63 BC157878 AAI57879 BC171888 AAI71888 BC172354 AAI72354 XM_006715087 XP_006715150 XM_006725485 XP_006725548 XM_006725487 XP_006725550 XM_006725701 XP_006725764 XM_006725818 XP_006725881 XM_006725910 XP_006725973 XM_006726000 XP_006726063 XM_006726093 XP_006726156 XM_011514570 XP_011512872 XM_011547248 XP_011545550 XM_011547249 XP_011545551 XM_011548049 XP_011546351 XM_011548432 XP_011546734 NM_001109809 NP_001103279 |
Function | Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (By similarity). Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. {ECO:0000250, ECO:0000269|PubMed:18622393}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Binds various differentially methylated regions (DMR), including the SNRPN DMR. {ECO:0000250}. |
Mouse Zfp57 peptide - ab45340 from Abcam
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ZFP57 Antibody Blocking Peptide - LS-E5764 from LifeSpan Bioscience
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ZFP57 Antibody Blocking Peptide - LS-E11170 from LifeSpan Bioscience
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ZFP57-Antibody-Center-Blocking-Peptide - BP18299c from Abgent, a WuXi AppTec company
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ZFP57 Blocking Peptide - 33R-6161 from Fitzgerald
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ZFP57 Blocking Peptide - 33R-5989 from Fitzgerald
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Recombinant Human Zinc finger protein 57 homolog(ZFP57) - CSB-YP865138HU CSB-EP865138HU CSB-BP865138HU CSB-MP865138HU from Cusabio
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ZFP57 (N-term HIS tag) - TP760690 from Acris Antibodies
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Zinc finger protein 57 homolog (ZFP57) , Recombinant Protein - MBS1383737 from MyBioSource
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ZFP57 Recombinant Protein Antigen - NBP1-94138PEP from Novus Biologicals
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ZFP57 Peptide, Human - M34GP17798H from Creative Peptides
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Recombinant Human ZFP57 Protein, His-tagged - ZFP57-296H from Creative Biomart
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