Gene Symbol | ZFP57 |
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Entrez Gene | 346171 |
Alt Symbol | C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2 |
Species | Human |
Gene Type | protein-coding |
Description | ZFP57 zinc finger protein |
Other Description | zfp-57|zinc finger protein 57 homolog|zinc finger protein 698 |
Swissprots | B0S894 Q5SSB1 Q9NU63 B0V254 B2RXJ7 |
Accessions | CAB89275 Q9NU63 BC157878 AAI57879 BC171888 AAI71888 BC172354 AAI72354 XM_006715087 XP_006715150 XM_006725485 XP_006725548 XM_006725487 XP_006725550 XM_006725701 XP_006725764 XM_006725818 XP_006725881 XM_006725910 XP_006725973 XM_006726000 XP_006726063 XM_006726093 XP_006726156 XM_011514570 XP_011512872 XM_011547248 XP_011545550 XM_011547249 XP_011545551 XM_011548049 XP_011546351 XM_011548432 XP_011546734 NM_001109809 NP_001103279 |
Function | Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (By similarity). Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. {ECO:0000250, ECO:0000269|PubMed:18622393}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Binds various differentially methylated regions (DMR), including the SNRPN DMR. {ECO:0000250}. |
ZFP57 (G-16) - sc-169865 from Santa Cruz Biotechnology
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ZFP57 (U-18) - sc-102171 from Santa Cruz Biotechnology
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Anti-Zfp57 antibody - ab50944 from Abcam
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Anti-Zfp57 antibody - ab173866 from Abcam
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Anti-ZFP57 Antibody (aa269-296, AP) - LS-C242974 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (aa269-296, APC) - LS-C242975 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (aa269-296, Biotin) - LS-C242976 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (aa269-296, FITC) - LS-C242977 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (aa269-296, PE) - LS-C242978 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (aa268-296) - LS-C326486 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (aa269-296, Azide-free, HRP) - LS-C247298 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (aa29-78) - LS-C30031 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (N-Terminus) - LS-C201260 from LifeSpan Bioscience
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Anti-ZFP57 Antibody (aa269-296) - LS-C157405 from LifeSpan Bioscience
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ZFP57 Antibody - NBP1-91520 from Novus Biologicals
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ZFP57 Antibody - NBP1-91550 from Novus Biologicals
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ZFP57 Antibody - NBP1-94138 from Novus Biologicals
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ZFP57 Polyclonal Antibody - bs-12252R from Bioss
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Rabbit Anti-ZFP57 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12252R-A350 from Bioss
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Rabbit Anti-ZFP57 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12252R-A488 from Bioss
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Rabbit Anti-ZFP57 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12252R-A555 from Bioss
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Rabbit Anti-ZFP57 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12252R-A647 from Bioss
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Rabbit Anti-ZFP57 Polyclonal Antibody, Cy3 Conjugated - bs-12252R-Cy3 from Bioss
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Rabbit Anti-ZFP57 Polyclonal Antibody, Cy5 Conjugated - bs-12252R-Cy5 from Bioss
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Rabbit Anti-ZFP57 Polyclonal Antibody, Cy5.5 Conjugated - bs-12252R-Cy5.5 from Bioss
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