HPGD

Gene Symbol	HPGD
Entrez Gene	3248
Alt Symbol	15-PGDH, PGDH, PGDH1, PHOAR1, SDR36C1
Species	Human
Gene Type	protein-coding
Description	hydroxyprostaglandin dehydrogenase 15-(NAD)
Other Description	15-hydroxyprostaglandin dehydrogenase [NAD(+)]|NAD+-dependent 15-hydroxyprostaglandin dehydrogenase|prostaglandin dehydrogenase 1|short chain dehydrogenase/reductase family 36C member 1|short chain dehydrogenase/reductase family 36C, member 1
Swissprots	Q12998 B4DV57 E7EV11 D3DP43 B4DTA4 B4DU74 Q06F08 O00749 P15428
Accessions	AAF29493 ABI75347 CAY55949 EAX04734 EAX04735 EAX04736 EAX04737 P15428 AI435471 AK058013 AK296642 BAH12408 AK300125 BAG61916 AK300524 BAG62236 AK300940 BAG62569 AK314624 BAG37190 BC007691 BC018986 AAH18986 DC420578 J05594 AAA89174 L76465 AAA89175 U63296 AAB53034 X82460 CAA57843 XM_011531907 XP_011530209 XR_938728 NM_000860 NP_000851 NM_001145816 NP_001139288 NM_001256301 NP_001243230 NM_001256305 NP_001243234 NM_001256306 NP_001243235 NM_001256307 NP_001243236
Function	Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells. {ECO:0000269|PubMed:10837478, ECO:0000269|PubMed:15574495, ECO:0000269|PubMed:16828555}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Detected in colon epithelium (at protein level). {ECO:0000269|PubMed:15574495}.
Top Pathways	Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Prostaglandin dehydrogenase 1 full length protein - ab99298 from Abcam Category Protein Source E. coli Species Human

Prostaglandin dehydrogenase 1 peptide (255-266) - ab45650 from Abcam Category Peptide Species Human

15-PGDH / HPGD Antibody Blocking Peptide - LS-E25798 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

15-PGDH / HPGD Antibody Blocking Peptide - LS-E22314 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

15-PGDH / HPGD Antibody Blocking Peptide - LS-E8466 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

15-PGDH/HPGD Recombinant Protein - H00003248-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human 15-PGDH/HPGD Protein - NBP1-48591 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 50 µg, 250 µg Source E. coli Species Human

HPGD-Antibody-C-term-Blocking-Peptide - BP6794b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

15-PGDH blocking peptide - GTX89634-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human 15-PGDH/HPGD, CF - 5660-DH-010 from R&D Systems Category Protein Source E. coli-derived, Met1-Gln266, with a C-terminal 6-His tag

HPGD Protein (OPPA02531) - OPPA02531 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human HPGD protein - orb168515 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli

15-PGDH protein - orb197671 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

HPGD Blocking Peptide - 33R-10315 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HPGD protein (His tag) - 80R-1481 from Fitzgerald Category Protein Prices $255.00 Sizes 50 µg Source E.coli

Prostaglandin Dehydrogenase 1 Peptide - AC21-0629-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

HPGD (1-266, His-tag) - AR09657PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

HPGD (1-266, His-tag) - AR09657PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

HPGD - H00003248-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HPGD - H00003248-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human 15-PGDH - 230-00575-10 from RayBiotech Category Protein Prices $110.00 Sizes 10 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human 15-PGDH - 230-00575-50 from RayBiotech Category Protein Prices $224.00 Sizes 50 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human 15-PGDH - 230-00575-100 from RayBiotech Category Protein Prices $336.00 Sizes 100 µg Source Escherichia coli (E.coli) Species Human

HPGD, 1-266aa, Human, His tag, E.coli - 01-1898 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

HPGD Peptide - 45-070P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

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