HPGD

Gene Symbol HPGD
Entrez Gene 3248
Alt Symbol 15-PGDH, PGDH, PGDH1, PHOAR1, SDR36C1
Species Human
Gene Type protein-coding
Description hydroxyprostaglandin dehydrogenase 15-(NAD)
Other Description 15-hydroxyprostaglandin dehydrogenase [NAD(+)]|NAD+-dependent 15-hydroxyprostaglandin dehydrogenase|prostaglandin dehydrogenase 1|short chain dehydrogenase/reductase family 36C member 1|short chain dehydrogenase/reductase family 36C, member 1
Swissprots Q12998 B4DV57 E7EV11 D3DP43 B4DTA4 B4DU74 Q06F08 O00749 P15428
Accessions AAF29493 ABI75347 CAY55949 EAX04734 EAX04735 EAX04736 EAX04737 P15428 AI435471 AK058013 AK296642 BAH12408 AK300125 BAG61916 AK300524 BAG62236 AK300940 BAG62569 AK314624 BAG37190 BC007691 BC018986 AAH18986 DC420578 J05594 AAA89174 L76465 AAA89175 U63296 AAB53034 X82460 CAA57843 XM_011531907 XP_011530209 XR_938728 NM_000860 NP_000851 NM_001145816 NP_001139288 NM_001256301 NP_001243230 NM_001256305 NP_001243234 NM_001256306 NP_001243235 NM_001256307 NP_001243236
Function Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells. {ECO:0000269|PubMed:10837478, ECO:0000269|PubMed:15574495, ECO:0000269|PubMed:16828555}.
Subcellular Location Cytoplasm.
Tissue Specificity Detected in colon epithelium (at protein level). {ECO:0000269|PubMed:15574495}.
Top Pathways Transcriptional misregulation in cancer

PGDH CRISPR/Cas9 KO Plasmid (h) - sc-402622 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGDH HDR Plasmid (h) - sc-402622-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGDH Double Nickase Plasmid (h) - sc-402622-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGDH Double Nickase Plasmid (h2) - sc-402622-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGDH CRISPR Activation Plasmid (h) - sc-402622-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGDH CRISPR Activation Plasmid (h2) - sc-402622-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGDH Lentiviral Activation Particles (h) - sc-402622-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGDH Lentiviral Activation Particles (h2) - sc-402622-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGDH siRNA (h) - sc-61330 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PGDH shRNA Plasmid (h) - sc-61330-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PGDH shRNA (h) Lentiviral Particles - sc-61330-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

15-PGDH/HPGD RNAi - H00003248-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU072531 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10275 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10275 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10319 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10319

HPGD siRNA (Human) - CRH2227 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HPGD - MBS8202744 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HPGD (NM_000860.5) - SHH314593 from Creative biogene

Category siRNA
Species Reactivities Human

HPGD shRNA Plasmid (Human) - CHH2227 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HPGD miRNA 3'UTR clone - MiUTR3H-04321 from Creative biogene

Species Reactivities Human

HPGD miRNA 3'UTR clone - MiUTR3H-04322 from Creative biogene

Species Reactivities Human
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