Gene Symbol | DNTT |
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Entrez Gene | 1791 |
Alt Symbol | TDT |
Species | Human |
Gene Type | protein-coding |
Description | DNA nucleotidylexotransferase |
Other Description | deoxynucleotidyltransferase, terminal|nucleosidetriphosphate:DNA deoxynucleotidylexotransferase|terminal addition enzyme|terminal deoxynucleotidyltransferase|terminal deoxyribonucleotidyltransferase|terminal transferase |
Swissprots | P04053 Q5W103 Q53FH1 Q96E50 |
Accessions | AAA61137 EAW49979 P04053 AB046378 BAB72001 AK130771 AK223317 BAD97037 AK313615 BC012920 AAH12920 DQ891465 ABM82391 DQ894645 ABM85571 K01919 AAA61136 M20694 AAA53100 M20695 M20696 M20697 M20698 M20699 M20700 M20701 M20702 M20703 M22968 M26144 AAA74588 XM_011539420 XP_011537722 NM_001017520 NP_001017520 NM_004088 NP_004079 |
Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
Subcellular Location | Nucleus. |
Top Pathways | Hematopoietic cell lineage, Non-homologous end-joining |
Human TdT protein fragment - ab152345 from Abcam
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DNTT / TdT Antibody Blocking Peptide - LS-E1071 from LifeSpan Bioscience
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DNTT / TdT Antibody Blocking Peptide - LS-E3312 from LifeSpan Bioscience
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DNTT / TdT Antibody Blocking Peptide - LS-E18670 from LifeSpan Bioscience
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DNTT / TdT Antibody Blocking Peptide - LS-E18671 from LifeSpan Bioscience
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Recombinant Human TdT Protein - H00001791-Q01 from Novus Biologicals
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TdT-Antibody-C-term-Blocking-peptide - BP11561b from Abgent, a WuXi AppTec company
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TDT-Antibody-N-term-Blocking-Peptide - BP14478a from Abgent, a WuXi AppTec company
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DNTT Blocking Peptide - 33R-3028 from Fitzgerald
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DNTT Blocking Peptide - 33R-5388 from Fitzgerald
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DNTT / TDT - H00001791-Q01-10 from Acris Antibodies
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DNTT / TDT - H00001791-Q01-25 from Acris Antibodies
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DNTT / TDT Control Peptide - AP10335CP-N from Acris Antibodies
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DNTT,TDT fusion protein - ag0426 from Proteintech Group
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DNTT,TDT fusion protein - ag10988 from Proteintech Group
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DNTT,TDT fusion protein - Ag11235 from Proteintech Group
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Recombinant Human Deoxynucleotidyltransferase, Terminal - DNTT-563H from Creative Biomart
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Recombinant Human DNA nucleotidylexotransferase(DNTT) - CSB-YP007088HU CSB-EP007088HU CSB-BP007088HU CSB-MP007088HU from Cusabio
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DNTT Peptide, Human - M34GP04467H from Creative Peptides
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TDT Recombinant Protein (OPCA01567) - OPCA01567 from Aviva Systems Biology
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Human TDT protein - orb358084 from Biorbyt
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Recombinant Human Terminal Deoxynucleotidyltransferase/TdT - 230-00266-10 from RayBiotech
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Terminal Transferase (20,000 U/ml) - M1249 from Biovision
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Recombinant human DNA nucleotidylexotransferase - AP70241 from Signalway Antibody
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DNA nucleotidylexotransferase, Recombinant Protein - MBS9420182 from MyBioSource
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