CASP4

Gene Symbol CASP4
Entrez Gene 837
Alt Symbol ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
Species Human
Gene Type protein-coding
Description caspase 4, apoptosis-related cysteine peptidase
Other Description CASP-4|ICE(rel)-II|apoptotic cysteine protease Mih1/TX|caspase 4, apoptosis-related cysteine protease|caspase-4|protease ICH-2|protease TX
Swissprots A2NHL8 A2NHM0 P49662
Accessions ABR09278 CAA03154 EAW67050 EAW67051 EAW67052 EAW67053 P49662 AI128358 AK057094 BAG51861 AK225751 AK296081 BAG58837 AK304222 BAG65094 AL050391 CAB43686 BC008060 BC017839 AAH17839 CN261701 DQ891983 ABM82909 DQ895173 ABM86099 U25804 AAA86890 U28014 AAA75171 U28976 AAC99850 U28977 AAC99851 U28978 AAC99852 U28979 AAC99853 Z48810 CAA88750 XM_011543019 XP_011541321 NM_001225 NP_001216 NM_033306 NP_150649 NM_033307
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Involved in ER-stress induced apoptosis. Cleaves caspase-1. {ECO:0000269|PubMed:15123740, ECO:0000269|Ref.14}.
Subcellular Location Endoplasmic reticulum membrane. Mitochondrion.
Tissue Specificity Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.

Caspase-4 Antibody - 4450 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from KARPAS-299, THP-1 and IM-9 cells using Caspase-4 Antibody.

caspase-4 (4B9) - sc-56056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
caspase-4 (4B9): sc-56056. Western blot analysis of caspase-4 expression in ECV304 (A), HeLa (B) and UV-treated HeLa (C) whole cell lysates.

caspase-4 p10 (C-19) - sc-1227 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

caspase-4 p20 (N-15) - sc-1229 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
caspase-4 p20: sc-1229. Western blot analysis of caspase-4 p20 expression in WEHI-231 whole cell lysate.

caspase-4/5 p10 (H-60) - sc-28229 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
caspase-4/5 p10 (H-60): sc-28229. Western blot analysis of caspase-4 and caspase-5 precursor expression in Jurkat whole cell lysate.

cleaved caspase-4 p10 (h290) - sc-22174 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cleaved caspase-4 p10 (h290): sc-22174. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

cleaved caspase-4/5 p20 (h270) - sc-22173 from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Goat
Clonality Polyclonal

Anti-Caspase 4 antibody - ab25898 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Caspase 4 antibody (ab25898) at 0.5 µg/mlLane 2 : Anti-Caspase 4 antibody (ab25898) at 1 µg/mlLane 1 : Ramos cell lysateLane 2 : Ramos cell lysate

Anti-Caspase 4 antibody - ab97318 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Caspase 4 antibody (ab97318) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-Caspase 4 antibody - ab25897 from Abcam

Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Caspase 4 antibody (ab25897) at 1 µg/mlLane 2 : Anti-Caspase 4 antibody (ab25897) at 2 µg/mlLane 1 : Human spleen cell lysateLane 2 : Human spleen cell lysate

Anti-Caspase 4 antibody - ab22687 from Abcam

Prices $372.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-Caspase 4 antibody - ab75182 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Caspase 4 antibody (ab75182) at 1/500 dilutionLane 1 : extracts from Jurkat cellsLane 2 : extracts from Jurkat cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Caspase 4 antibody - ab135285 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Caspase 4 antibody (ab135285) at 1/500 dilution + K562 cell extracts at 30 µg

Anti-Caspase 4 antibody - ab10447 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Caspase 4 antibody - ab115192 from Abcam

Prices $370.00
Sizes 25 µg
Host Rabbit
Clonality Polyclonal

Anti-Caspase 4 antibody - ab137730 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Caspase 4 antibody (ab137730) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-Caspase 4 antibody [CAS4] - ab10446 from Abcam

Prices $372.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone CAS4

Anti-CASP4 / Caspase 4 Antibody - LS-C35306 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-CASP4 / Caspase 4 Antibody (aa202-217) - LS-C35304 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CASP4 / Caspase 4 Antibody (C-Terminus) - LS-C35307 from LifeSpan Bioscience

Prices $590.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CASP4 / Caspase 4 Antibody - LS-C26866 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of caspase-4 in human spleen cells with caspase-4 antibody at (A) 1 and (B) 2 g/ml

Anti-CASP4 / Caspase 4 Antibody (aa85-101) - LS-C63131 from LifeSpan Bioscience

Prices $255.00, $355.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CASP4 / Caspase 4 Antibody (aa119-133) - LS-C77878 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal

Anti-CASP4 / Caspase 4 Antibody (aa118-132) - LS-C54611 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of Human Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CASP4 / Caspase 4 Antibody (N-Terminus) - LS-C48312 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot of Caspase 4 antibody LS-C48312.
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