CASP4

Gene Symbol	CASP4
Entrez Gene	837
Alt Symbol	ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
Species	Human
Gene Type	protein-coding
Description	caspase 4, apoptosis-related cysteine peptidase
Other Description	CASP-4|ICE(rel)-II|apoptotic cysteine protease Mih1/TX|caspase 4, apoptosis-related cysteine protease|caspase-4|protease ICH-2|protease TX
Swissprots	A2NHL8 A2NHM0 P49662
Accessions	ABR09278 CAA03154 EAW67050 EAW67051 EAW67052 EAW67053 P49662 AI128358 AK057094 BAG51861 AK225751 AK296081 BAG58837 AK304222 BAG65094 AL050391 CAB43686 BC008060 BC017839 AAH17839 CN261701 DQ891983 ABM82909 DQ895173 ABM86099 U25804 AAA86890 U28014 AAA75171 U28976 AAC99850 U28977 AAC99851 U28978 AAC99852 U28979 AAC99853 Z48810 CAA88750 XM_011543019 XP_011541321 NM_001225 NP_001216 NM_033306 NP_150649 NM_033307
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Involved in ER-stress induced apoptosis. Cleaves caspase-1. {ECO:0000269|PubMed:15123740, ECO:0000269|Ref.14}.
Subcellular Location	Endoplasmic reticulum membrane. Mitochondrion.
Tissue Specificity	Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Caspase 4 full length protein - ab51994 from Abcam Category Protein Prices $471.00 Sizes 100 units Source E. coli Species Human

Caspase 13 peptide - ab7884 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Caspase 4 peptide - ab45616 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Caspase 4 peptide - ab71984 from Abcam Category Peptide Prices $176.00 Sizes 50 µg Species Human

Human Caspase 4 peptide - ab39725 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

CASP14 / Caspase 14 Antibody Blocking Peptide - LS-E29982 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CASP4 / Caspase 4 Antibody Blocking Peptide - LS-E25767 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CASP4 / Caspase 4 Antibody Blocking Peptide - LS-E30116 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CASP4 / Caspase 4 Antibody Blocking Peptide - LS-E30117 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CASP4 / Caspase 4 Antibody Blocking Peptide - LS-E21585 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Caspase-4 Protein - H00000837-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Caspase-4 Recombinant Protein - P4035 from Novus Biologicals Category Protein Prices $449.00 Sizes 1 unit Species Human

Caspase-4 Peptide - NBP1-77208PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Caspase-4 Blocking Peptide - NBP1-76602PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Caspase-4 Blocking Peptide - NBP1-76812PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Caspase-4 Protein - NBP1-99214 from Novus Biologicals Category Protein Species Human

Caspase-4 Protein - NBP1-99585 from Novus Biologicals Category Protein Species Human

Caspase 4 recombinant protein - GTX65033 from GeneTex Category Protein Prices $329.00 Sizes 100 unit Source E. coli Species Human

Caspase 4 recombinant protein - GTX65034 from GeneTex Category Protein Prices $219.00 Sizes 25 unit Source E. coli Species Human

Caspase 4 blocking peptide - GTX89618-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Caspase-4 Inhibitor Z-YVAD-FMK - FMK005 from R&D Systems Category Peptide Prices $215.00 Sizes 1 mg

CASP4 Blocking Peptide - 33R-3333 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Caspase 4 Blocking Peptide - 33R-10598 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Caspase 4 protein - 30R-2320 from Fitzgerald Category Protein Prices $275.00, $445.00 Sizes 25 units, 100 units Source E.coli Species Human

Human Caspase 4 Protein - abx065763 from Abbexa Category Protein Source E.coli Species Human

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