Gene Symbol | HAX1 |
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Entrez Gene | 10456 |
Alt Symbol | HCLSBP1, HS1BP1, SCN3 |
Species | Human |
Gene Type | protein-coding |
Description | HCLS1 associated protein X-1 |
Other Description | HAX-1|HCLS1 (and PKD2) associated protein|HCLS1-associated protein X-1|HS1 binding protein|HS1-associating protein X-1|HS1-binding protein 1|HSP1BP-1 |
Swissprots | Q5VYD7 A8W4X0 O00165 Q5VYD5 B4DUJ7 Q96AU4 A8W4W9 Q9BS80 |
Accessions | EAW53212 O00165 AK290626 BAF83315 AK294298 BAG57580 AK300676 BAG62359 AK310000 AK311450 AK313291 BC005240 AAH05240 BC014314 AAH14314 BC015209 AAH15209 BC016730 AAH16730 BF668367 EU190982 ABW73998 EU190983 ABW73999 HQ447125 ADQ31612 JF432154 ADZ15371 U68566 AAB51196 NM_001018837 NP_001018238 NM_006118 NP_006109 |
Function | Promotes cell survival. Potentiates GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. May regulate intracellular calcium pools. {ECO:0000269|PubMed:15339924, ECO:0000269|PubMed:16857965, ECO:0000269|PubMed:17545607, ECO:0000269|PubMed:18319618, ECO:0000269|PubMed:18971376, ECO:0000269|PubMed:9058808}. |
Subcellular Location | Mitochondrion. Endoplasmic reticulum. Nucleus membrane. Cytoplasmic vesicle {ECO:0000250}. Sarcoplasmic reticulum {ECO:0000250}. |
Tissue Specificity | Ubiquitous. Up-regulated in oral cancers. {ECO:0000269|PubMed:17545607, ECO:0000269|PubMed:9058808}. |
HAX-1 (B-11) - sc-166845 from Santa Cruz Biotechnology
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HAX-1 (FL-279) - sc-28268 from Santa Cruz Biotechnology
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HAX-1 (N-17) - sc-16636 from Santa Cruz Biotechnology
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HAX-1 (E-20) - sc-34273 from Santa Cruz Biotechnology
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HAX-1 (P-20) - sc-16637 from Santa Cruz Biotechnology
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Anti-HAX1 antibody - ab137613 from Abcam
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Anti-HAX1 antibody - ab78939 from Abcam
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Anti-HAX1 antibody - ab87185 from Abcam
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Anti-HAX1 antibody - ab81973 from Abcam
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Anti-HAX1 antibody [9G3D11] - ab79723 from Abcam
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Anti-HAX1 antibody - C-terminal - ab170672 from Abcam
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Anti-HAX-1 Antibody (HRP) - LS-C211852 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (Internal) - LS-C209396 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (FITC) - LS-C211856 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (Biotin) - LS-C211857 from LifeSpan Bioscience
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Anti-HAX-1 Antibody - LS-C211853 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (aa161-190, AP) - LS-C258286 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (aa161-190, APC) - LS-C258290 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (aa107-156) - LS-C116450 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (aa76-174) - LS-C308184 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (aa161-190, PE) - LS-C258289 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (aa160-190) - LS-C321882 from LifeSpan Bioscience
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Anti-HAX-1 Antibody - LS-C341649 from LifeSpan Bioscience
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Anti-HAX-1 Antibody (aa161-190) - LS-C166799 from LifeSpan Bioscience
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Anti-HAX-1 Antibody - LS-C334130 from LifeSpan Bioscience
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