Gene Symbol | HAX1 |
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Entrez Gene | 10456 |
Alt Symbol | HCLSBP1, HS1BP1, SCN3 |
Species | Human |
Gene Type | protein-coding |
Description | HCLS1 associated protein X-1 |
Other Description | HAX-1|HCLS1 (and PKD2) associated protein|HCLS1-associated protein X-1|HS1 binding protein|HS1-associating protein X-1|HS1-binding protein 1|HSP1BP-1 |
Swissprots | Q5VYD7 A8W4X0 O00165 Q5VYD5 B4DUJ7 Q96AU4 A8W4W9 Q9BS80 |
Accessions | EAW53212 O00165 AK290626 BAF83315 AK294298 BAG57580 AK300676 BAG62359 AK310000 AK311450 AK313291 BC005240 AAH05240 BC014314 AAH14314 BC015209 AAH15209 BC016730 AAH16730 BF668367 EU190982 ABW73998 EU190983 ABW73999 HQ447125 ADQ31612 JF432154 ADZ15371 U68566 AAB51196 NM_001018837 NP_001018238 NM_006118 NP_006109 |
Function | Promotes cell survival. Potentiates GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. May regulate intracellular calcium pools. {ECO:0000269|PubMed:15339924, ECO:0000269|PubMed:16857965, ECO:0000269|PubMed:17545607, ECO:0000269|PubMed:18319618, ECO:0000269|PubMed:18971376, ECO:0000269|PubMed:9058808}. |
Subcellular Location | Mitochondrion. Endoplasmic reticulum. Nucleus membrane. Cytoplasmic vesicle {ECO:0000250}. Sarcoplasmic reticulum {ECO:0000250}. |
Tissue Specificity | Ubiquitous. Up-regulated in oral cancers. {ECO:0000269|PubMed:17545607, ECO:0000269|PubMed:9058808}. |
Human HAX1 full length protein - ab132989 from Abcam
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Human HAX1 full length protein - ab140544 from Abcam
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HAX-1 Antibody Blocking Peptide - LS-E1573 from LifeSpan Bioscience
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HAX-1 Antibody Blocking Peptide - LS-E18724 from LifeSpan Bioscience
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HAX-1 Antibody Blocking Peptide - LS-E18723 from LifeSpan Bioscience
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HAX-1 Antibody Blocking Peptide - LS-E26978 from LifeSpan Bioscience
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HAX-1 Antibody Blocking Peptide - LS-E30539 from LifeSpan Bioscience
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HAX-1 Antibody Blocking Peptide - LS-E30540 from LifeSpan Bioscience
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HAX-1 Partial Recombinant Protein - H00010456-Q01 from Novus Biologicals
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HAX-1 Recombinant Protein - H00010456-P01 from Novus Biologicals
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Recombinant Human HAX-1 Protein - NBP2-23101 from Novus Biologicals
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HAX-1 Blocking Peptide - NBP1-76361PEP from Novus Biologicals
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HAX-1 Blocking Peptide - NBP1-76362PEP from Novus Biologicals
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HAX1-Antibody-C-term-Blocking-peptide - BP12311b from Abgent, a WuXi AppTec company
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HAX1 blocking peptide - GTX88468-PEP from GeneTex
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Human HAX1 protein - orb245181 from Biorbyt
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Human HAX1 protein - orb191088 from Biorbyt
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HAX1 Blocking Peptide - 33R-5266 from Fitzgerald
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HAX1 Blocking Peptide - 33R-7672 from Fitzgerald
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HAX1 protein (His tag) - 80R-2673 from Fitzgerald
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HAX1 Peptide - AC21-1805-P from Abcore
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HAX1 (1-279, His-tag) - AR50793PU-N from Acris Antibodies
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HAX1 (1-279, His-tag) - AR50793PU-S from Acris Antibodies
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HAX1 - H00010456-P01-10 from Acris Antibodies
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HAX1 - H00010456-P01-25 from Acris Antibodies
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