SPEG

Gene Symbol SPEG
Entrez Gene 10290
Alt Symbol APEG-1, APEG1, BPEG, CNM5, SPEGalpha, SPEGbeta
Species Human
Gene Type protein-coding
Description SPEG complex locus
Other Description aortic preferentially expressed gene 1|aortic preferentially expressed protein 1|nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury|striated muscle preferentially expressed protein kinase
Swissprots Q695L1 A8K0G6 A8MRU0 Q6ZQW1 Q9P2P9 Q15772 Q6FGA6 Q27J74 Q6ZTL8
Accessions AAY15052 EAW70742 EAW70743 EAW70744 EAW70745 EAW70746 EAW70747 EAW70748 EAW70749 EAW70750 EAW70751 Q15772 AB037718 BAA92535 AK055387 AK098307 AK126500 BAC86568 AK128689 AK129604 AK289531 BAF82220 AL512705 AL535839 AY603755 AAT80901 BC006346 AAH06346 BM677138 CR542201 CAG46998 DA063220 DQ395348 ABD61734 U57099 AAC50599 XM_005246237 XP_005246294 XM_005246239 XP_005246296 XM_005246240 XP_005246297 XM_005246241 XP_005246298 XM_005246242 XP_005246299 XM_006712189 XP_006712252 XM_006712193 XP_006712256 XM_011510479 XP_011508781 XM_011510480 XP_011508782 XM_011510481 XP_011508783 XM_011510482 XP_011508784 XM_011510483 XP_011508785 XM_011510484 XP_011508786 XM_011510485 XP_011508787 XM_011510486 XP_011508788 NM_001173476 NP_001166947 NM_005876 NP_005867
Function Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.
Subcellular Location Isoform 3: Nucleus.
Tissue Specificity Isoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC in vivo. In response to vascular injuries ASMC dedifferentiate and change from a quiescent and contractile phenotype to a proliferative and synthetic phenotype. This proliferation of vascular smooth muscle cells is one of the most prominent features of atherosclerosis. {ECO:0000269|PubMed:15185077, ECO:0000269|PubMed:8663449}.

Human-SPEG-cDNA-Clone - DC01950 from Abgent, a WuXi AppTec company

Prices $152.55
Sizes 10 µg
Species Human
Accession BC006346

SPEG - MBS1271283 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC006346

Human SPEG cDNA clone(NM_001173476.1) - CDFH018472 from Creative Biomart

Species Human
Accession NM_001173476.1

Human SPEG cDNA clone(NM_005876.4) - CDFH018474 from Creative Biomart

Species Human
Accession NM_005876.4

human SPEG ORF clone - CDCH085186 from Creative Biomart

Species Human
Accession NM_001173476

human SPEG ORF clone - CDCH085187 from Creative Biomart

Species Human
Accession NM_001173476

Human SPEG ORF Clone(NM_005876.4) - CDCR291509 from Creative Biomart

Species Human
Accession NM_005876.4

Human SPEG ORF Clone(NM_005876.4) - CDCR291510 from Creative Biomart

Species Human
Accession NM_005876.4

Human SPEG ORF Clone(NM_001173476.1) - CDCR356763 from Creative Biomart

Species Human
Accession NM_001173476.1

Human SPEG ORF Clone(NM_001173476.1) - CDCR356764 from Creative Biomart

Species Human
Accession NM_001173476.1

Human SPEG ORF Clone(NM_005876.4) - CDCL176824 from Creative Biomart

Species Human
Accession NM_005876.4

Human SPEG ORF Clone(NM_005876.4) - CDCR291509 from Creative biogene

Species Human

Human SPEG ORF Clone(NM_001173476.1) - CDCR356763 from Creative biogene

Species Human

Human SPEG ORF Clone (BC006346) - CDCS409037 from Creative biogene

Species Human
Accession Q15772

Human SPEG cDNA Clone(NM_001173476.1) - CDFH018472 from Creative biogene

Species Human

Human SPEG cDNA Clone(NM_005876.4) - CDFH018474 from Creative biogene

Species Human
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