SPEG

Gene Symbol	SPEG
Entrez Gene	10290
Alt Symbol	APEG-1, APEG1, BPEG, CNM5, SPEGalpha, SPEGbeta
Species	Human
Gene Type	protein-coding
Description	SPEG complex locus
Other Description	aortic preferentially expressed gene 1|aortic preferentially expressed protein 1|nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury|striated muscle preferentially expressed protein kinase
Swissprots	Q695L1 A8K0G6 A8MRU0 Q6ZQW1 Q9P2P9 Q15772 Q6FGA6 Q27J74 Q6ZTL8
Accessions	AAY15052 EAW70742 EAW70743 EAW70744 EAW70745 EAW70746 EAW70747 EAW70748 EAW70749 EAW70750 EAW70751 Q15772 AB037718 BAA92535 AK055387 AK098307 AK126500 BAC86568 AK128689 AK129604 AK289531 BAF82220 AL512705 AL535839 AY603755 AAT80901 BC006346 AAH06346 BM677138 CR542201 CAG46998 DA063220 DQ395348 ABD61734 U57099 AAC50599 XM_005246237 XP_005246294 XM_005246239 XP_005246296 XM_005246240 XP_005246297 XM_005246241 XP_005246298 XM_005246242 XP_005246299 XM_006712189 XP_006712252 XM_006712193 XP_006712256 XM_011510479 XP_011508781 XM_011510480 XP_011508782 XM_011510481 XP_011508783 XM_011510482 XP_011508784 XM_011510483 XP_011508785 XM_011510484 XP_011508786 XM_011510485 XP_011508787 XM_011510486 XP_011508788 NM_001173476 NP_001166947 NM_005876 NP_005867
Function	Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.
Subcellular Location	Isoform 3: Nucleus.
Tissue Specificity	Isoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC in vivo. In response to vascular injuries ASMC dedifferentiate and change from a quiescent and contractile phenotype to a proliferative and synthetic phenotype. This proliferation of vascular smooth muscle cells is one of the most prominent features of atherosclerosis. {ECO:0000269|PubMed:15185077, ECO:0000269|PubMed:8663449}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human APEG1 full length protein - ab160929 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human APEG1 protein fragment - ab160930 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

SPEG Antibody Blocking Peptide - LS-E27891 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human APEG1 Protein - H00010290-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human APEG1 Protein - H00010290-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human SPEG His tag protein - orb84303 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

APEG1 Peptide - AC21-2675-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

APEG-1 / SPEG - H00010290-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

APEG-1 / SPEG - H00010290-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

APEG-1 / SPEG - H00010290-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

APEG-1 / SPEG - H00010290-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SPEG Peptide - 43-082P from ProSci Category Peptide

SPEG fusion protein - Ag8330 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SPEG, His tagged - SPEG-3797H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human SPEG, GST-tagged - SPEG-2912H from Creative Biomart Category Protein Source E.coli Species Human

APEG-1 - PN201213 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source E. coli Species Human

Recombinant human Striated muscle preferentially expressed protein kinase - CSB-YP022529HU CSB-BP022529HU CSB-MP022529HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Striated muscle preferentially expressed protein kinase - CSB-EP022529HU from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Striated muscle preferentially expressed protein kinase(SPEG) - CSB-YP623013HU CSB-EP623013HU CSB-BP623013HU CSB-MP623013HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

APEG1/SPEG, Peptide - MBS427821 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human SPEG / APEG-1 Protein (His tag) - PKSH030334 from Elabscience Category Protein Source E. coli Species Human

APEG1 Recombinant Protein Antigen - NBP1-90134PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Human SPEG protein - orb244560 from Biorbyt Category Protein Prices $366.00, $595.00, $986.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

SPEG Peptide, Human - M34GP15032H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant human Striated muscle preferentially expressed protein kinase - AP70802 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

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