Gene Symbol | MED18 |
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Entrez Gene | 54797 |
Alt Symbol | p28b |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 18 |
Other Description | TRAP/mediator complex subunit p28b|mediator of RNA polymerase II transcription subunit 18|mediator of RNA polymerase II transcription, subunit 18 homolog |
Swissprots | D3DPM1 Q9BUE0 Q9NXU9 |
Accessions | EAX07699 EAX07700 EAX07701 EAX07702 Q9BUE0 AB107222 BAD06869 AK000052 BAA90910 AK296130 BAG58875 BC002694 AAH02694 BG752399 DA090416 XM_005245914 XP_005245971 NM_001127350 NP_001120822 NM_017638 NP_060108 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus {ECO:0000305}. |
Med18 (E-4) - sc-514415 from Santa Cruz Biotechnology
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Med18 (E-14) - sc-161835 from Santa Cruz Biotechnology
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Med18 (FL-208) - sc-367125 from Santa Cruz Biotechnology
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Anti-MED18 antibody - ab169700 from Abcam
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Anti-MED18 antibody - ab74937 from Abcam
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Anti-MED18 Antibody (aa180-206, AP) - LS-C237508 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa180-206, Biotin) - LS-C237510 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa180-206, Azide-free, HRP) - LS-C248791 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa180-206, APC) - LS-C237509 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa180-206, PE) - LS-C237514 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa180-206, FITC) - LS-C237512 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa179-206) - LS-C322938 from LifeSpan Bioscience
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Anti-MED18 Antibody - LS-C311372 from LifeSpan Bioscience
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Anti-MED18 Antibody - LS-C311371 from LifeSpan Bioscience
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Anti-MED18 Antibody (Val102) - LS-C340863 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa82-131) - LS-C145725 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa180-206) - LS-C158122 from LifeSpan Bioscience
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Anti-MED18 Antibody (C-Terminus) - LS-C287634 from LifeSpan Bioscience
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Anti-MED18 Antibody (C-Terminus) - LS-C285955 from LifeSpan Bioscience
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Anti-MED18 Antibody (aa70-119) - LS-C120076 from LifeSpan Bioscience
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MED18 Antibody - NBP2-17257 from Novus Biologicals
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MED18 Antibody - NBP1-83673 from Novus Biologicals
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MED18 Antibody - H00054797-D01P from Novus Biologicals
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MED18 Antibody - H00054797-B01 from Novus Biologicals
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MED18 Antibody - H00054797-B01P from Novus Biologicals
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