| Gene Symbol |
MED18
|
| Entrez Gene |
54797
|
| Alt Symbol |
p28b
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 18
|
| Other Description |
TRAP/mediator complex subunit p28b|mediator of RNA polymerase II transcription subunit 18|mediator of RNA polymerase II transcription, subunit 18 homolog
|
| Swissprots |
D3DPM1 Q9BUE0 Q9NXU9
|
| Accessions |
EAX07699 EAX07700 EAX07701 EAX07702 Q9BUE0 AB107222 BAD06869 AK000052 BAA90910 AK296130 BAG58875 BC002694 AAH02694 BG752399 DA090416 XM_005245914 XP_005245971 NM_001127350 NP_001120822 NM_017638 NP_060108
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|