| Gene Symbol |
ALDH18A1
|
| Entrez Gene |
5832
|
| Alt Symbol |
ARCL3A, GSAS, P5CS, PYCS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
aldehyde dehydrogenase 18 family, member A1
|
| Other Description |
aldehyde dehydrogenase family 18 member A1|delta-1-pyrroline-5-carboxylate synthase|delta-1-pyrroline-5-carboxylate synthetase|delta1-pyrroline-5-carboxlate synthetase|pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)
|
| Swissprots |
Q5T566 B2R5Q4 P54886 Q3KQU2 D3DR44 B7Z5X8 Q9UM72 B7ZLP1 Q5T567 B7Z350 O95952
|
| Accessions |
EAW49994 EAW49995 EAW49996 EAW49997 P54886 AK126355 AK225455 AK225465 AK226032 AK295487 BAH12086 AK299557 BAH13064 AK312271 BAG35201 AW467503 BC106054 AAI06055 BC117240 AAI17241 BC117242 AAI17243 BC143930 AAI43931 BU170321 CD642171 HQ258499 ADR83253 U68758 AAD00169 U76542 AAD17454 X94453 CAA64224 XM_006717933 XP_006717996 XM_011540001 XP_011538303 NM_001017423 NP_001017423 NM_002860 NP_002851
|
| Function |
Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine. {ECO:0000269|PubMed:10037775, ECO:0000269|PubMed:11092761}.
|
| Subcellular Location |
Mitochondrion inner membrane.
|
| Top Pathways |
Arginine and proline metabolism, Biosynthesis of amino acids
|
![Western Blot: ALDH18A1 Overexpression Lysate (Adult Normal) [NBP2-08064] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ALDH18A1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4209_ALDH18A1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08064-img0001.jpg)