Gene Symbol | ALDH18A1 |
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Entrez Gene | 5832 |
Alt Symbol | ARCL3A, GSAS, P5CS, PYCS |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 18 family, member A1 |
Other Description | aldehyde dehydrogenase family 18 member A1|delta-1-pyrroline-5-carboxylate synthase|delta-1-pyrroline-5-carboxylate synthetase|delta1-pyrroline-5-carboxlate synthetase|pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase) |
Swissprots | Q5T566 B2R5Q4 P54886 Q3KQU2 D3DR44 B7Z5X8 Q9UM72 B7ZLP1 Q5T567 B7Z350 O95952 |
Accessions | EAW49994 EAW49995 EAW49996 EAW49997 P54886 AK126355 AK225455 AK225465 AK226032 AK295487 BAH12086 AK299557 BAH13064 AK312271 BAG35201 AW467503 BC106054 AAI06055 BC117240 AAI17241 BC117242 AAI17243 BC143930 AAI43931 BU170321 CD642171 HQ258499 ADR83253 U68758 AAD00169 U76542 AAD17454 X94453 CAA64224 XM_006717933 XP_006717996 XM_011540001 XP_011538303 NM_001017423 NP_001017423 NM_002860 NP_002851 |
Function | Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine. {ECO:0000269|PubMed:10037775, ECO:0000269|PubMed:11092761}. |
Subcellular Location | Mitochondrion inner membrane. |
Top Pathways | Arginine and proline metabolism, Biosynthesis of amino acids |
P5CS protein (His-DHFR tag) - ab127829 from Abcam
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ALDH18A1 Antibody Blocking Peptide - LS-E20369 from LifeSpan Bioscience
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ALDH18A1 Antibody Blocking Peptide - LS-E27505 from LifeSpan Bioscience
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ALDH18A1 Antibody Blocking Peptide - LS-E9862 from LifeSpan Bioscience
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Recombinant Human ALDH18A1 Protein - H00005832-Q01 from Novus Biologicals
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ALDH18A1-Antibody-Center-Blocking-Peptide - BP8938c from Abgent, a WuXi AppTec company
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ALDH18A1 Blocking Peptide - 33R-8914 from Fitzgerald
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P5CS Peptide - AC21-2328-P from Abcore
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ALDH18A1 - H00005832-P01-10 from Acris Antibodies
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ALDH18A1 - H00005832-P01-25 from Acris Antibodies
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ALDH18A1 - H00005832-Q01-10 from Acris Antibodies
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ALDH18A1 - H00005832-Q01-25 from Acris Antibodies
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ALDH18A1 Peptide - 42-675P from ProSci
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ALDH18A1 fusion protein - Ag12100 from Proteintech Group
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Recombinant Human Aldehyde Dehydrogenase 18 Family, Member A1, His-tagged - ALDH18A1-486H from Creative Biomart
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Recombinant Human ALDH18A1, His-tagged - ALDH18A1-9549H from Creative Biomart
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Recombinant Human Delta-1-pyrroline-5-carboxylate synthase(ALDH18A1) - CSB-YP001564HU CSB-EP001564HU CSB-BP001564HU CSB-MP001564HU from Cusabio
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ALDH18A1 (transcript variant 1) - TP310726 from Acris Antibodies
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ALDH18A1, Peptide - MBS427422 from MyBioSource
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ALDH18A1 Recombinant Protein Antigen - NBP1-83325PEP from Novus Biologicals
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ALDH18A1 Recombinant Protein Antigen - NBP1-83324PEP from Novus Biologicals
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ALDH18A1 Peptide, Human - M34GP00475H from Creative Peptides
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ALDH18A1 Immunizing peptide - orb59895 from Biorbyt
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Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1), Recombinant Protein - MBS965169 from MyBioSource
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