Gene Symbol | CCDC39 |
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Entrez Gene | 339829 |
Alt Symbol | CILD14, FAP59 |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil domain containing 39 |
Other Description | coiled-coil domain-containing protein 39 |
Swissprots | Q9UFE4 B4E2H1 |
Accessions | Q9UFE4 AK304270 BAG65133 AL122120 CAB59277 BG205877 DC399927 NM_181426 NP_852091 |
Function | Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella (PubMed:21131972). Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly (PubMed:21131972). {ECO:0000250|UniProtKB:A8IQT2, ECO:0000269|PubMed:21131972}. |
Subcellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:21131972, ECO:0000269|PubMed:21131974}. Note=CCDC40 is required for localization to axonemes. {ECO:0000269|PubMed:21131974}. |
Tissue Specificity | Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis. {ECO:0000269|PubMed:21131972}. |
CCDC39 (D-16) - sc-99328 from Santa Cruz Biotechnology
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CCDC39 (E-13) - sc-99329 from Santa Cruz Biotechnology
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CCDC39 (N-16) - sc-99330 from Santa Cruz Biotechnology
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Anti-CCDC39 antibody - ab122269 from Abcam
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Anti-CCDC39 Antibody (aa770-798) - LS-C168418 from LifeSpan Bioscience
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Anti-CCDC39 Antibody (aa770-798, AP) - LS-C253661 from LifeSpan Bioscience
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Anti-CCDC39 Antibody (aa770-798, APC) - LS-C253662 from LifeSpan Bioscience
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Anti-CCDC39 Antibody (aa770-798, Biotin) - LS-C253663 from LifeSpan Bioscience
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Anti-CCDC39 Antibody (aa770-798, FITC) - LS-C253664 from LifeSpan Bioscience
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Anti-CCDC39 Antibody (aa770-798, Azide-free, HRP) - LS-C253665 from LifeSpan Bioscience
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Anti-CCDC39 Antibody (aa770-798) - LS-C320074 from LifeSpan Bioscience
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Anti-CCDC39 Antibody (aa770-798, PE) - LS-C253666 from LifeSpan Bioscience
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Anti-CCDC39 Antibody (aa64-113) - LS-C186840 from LifeSpan Bioscience
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CCDC39 Antibody - NBP1-90560 from Novus Biologicals
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CCDC39 Antibody - NBP2-33999 from Novus Biologicals
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CCDC39 Polyclonal Antibody - bs-8096R from Bioss
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Anti-CCDC39 antibody produced in rabbit - HPA035363 from Sigma-Aldrich
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ANTI-CCDC39 (C-TERM) antibody produced in rabbit - SAB1303996 from Sigma-Aldrich
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CCDC39 Antibody - N-terminal region (ARP67433_P050) - ARP67433_P050 from Aviva Systems Biology
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CCDC39 Antibody - C-terminal region (OAAB01059) - OAAB01059 from Aviva Systems Biology
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CCDC39-Antibody-C-term - AP11039b from Abgent, a WuXi AppTec company
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Anti -CCDC39, CT (CCDC39, Coiled-coil domain-containing protein 39) - 033322 from USBiological Life Science
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Anti -CCDC39, CT (CCDC39, Coiled-coil domain-containing protein 39) (AP) - 033322-AP from USBiological Life Science
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Anti -CCDC39, CT (CCDC39, Coiled-coil domain-containing protein 39) (APC) - 033322-APC from USBiological Life Science
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Anti -CCDC39, CT (CCDC39, Coiled-coil domain-containing protein 39) (Azide free) (HRP) - 033322-HRP from USBiological Life Science
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