SNX18

Gene Symbol	SNX18
Entrez Gene	112574
Alt Symbol	SH3PX2, SH3PXD3B, SNAG1
Species	Human
Gene Type	protein-coding
Description	sorting nexin 18
Other Description	SH3 and PX domain-containing protein 3B|sorting nexin associated golgi protein 1|sorting nexin-18|sorting nexin-associated Golgi protein 1
Swissprots	Q0VG02 Q05BB3 B4E2B3 Q96RF0 H7BXX3
Accessions	EAW54894 Q96RF0 AF395536 AAK82415 AI335241 AI669182 AK022059 AK057122 AK304195 BAG65075 BC060791 AAH60791 BC067860 AAH67860 BC117218 AAI17219 BC117220 AAI17221 BJ990551 BJ990552 CD722181 CN360136 CN479485 NM_001102575 NP_001096045 NM_001145427 NP_001138899 NM_052870 NP_443102
Function	Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane. {ECO:0000269|PubMed:18411244, ECO:0000269|PubMed:20427313, ECO:0000269|PubMed:21048941, ECO:0000269|PubMed:22718350}.
Subcellular Location	Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin- coated pits at a late stage of clathrin-coated vesicle formation.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SNX18 peptide - ab22972 from Abcam Category Peptide Species Human

SNX18 Antibody Blocking Peptide - LS-E4943 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SNX18 Antibody Blocking Peptide - LS-E25526 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SNX18 Antibody Blocking Peptide - LS-E21569 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SNX18 Antibody Blocking Peptide - LS-E21570 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SNX18 Antibody Blocking Peptide - LS-E18862 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SNX18-Antibody-C-term-Blocking-Peptide - BP17333b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SNX18 blocking peptide - GTX89870-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SNX18 Immunizing peptide - orb16803 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

SNAG1 Blocking Peptide - 33R-7486 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SNAG1 Blocking Peptide - 33R-5183 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SNAG1 Blocking Peptide - 33R-1256 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SNX18 Peptide - AC21-0355-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SNX18 Peptide - 46-401P from ProSci Category Peptide Species Human

SNX18 fusion protein - Ag17388 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SNX18 fusion protein - Ag16645 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SNX18, His-tagged - SNX18-2859H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Sorting nexin-18(SNX18) - CSB-YP850423HU CSB-EP850423HU CSB-BP850423HU CSB-MP850423HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Sorting Nexin Associated Golgi Protein 1 (SNAG1) - RPC857Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Sorting nexin-18 (SNX18) (transcript variant 1) - TP319205 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SNX18/SNAG1, Peptide - MBS425801 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

SNX18 Recombinant Protein Antigen - NBP1-82361PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SNX18 Peptide, Human - M34GP14850H from Creative Peptides Category Peptide Source Synthetic. Species Human

Sorting nexin-18 (SNX18), Recombinant Protein - MBS1473358 from MyBioSource Category Protein Prices $1,425.00, $1,425.00, $1,655.00, $1,655.00, $2,410.00, $2,410.00, $2,855.00, $2,855.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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