SULT2B1

Gene Symbol SULT2B1
Entrez Gene 6820
Alt Symbol HSST2
Species Human
Gene Type protein-coding
Description sulfotransferase family, cytosolic, 2B, member 1
Other Description ST2B1|alcohol sulfotransferase|hydroxysteroid sulfotransferase 2|sulfotransferase 2B1|sulfotransferase family cytosolic 2B member 1
Swissprots O00204 O75814 O00205
Accessions AAC78553 AAC78554 EAW52354 EAW52355 O00204 AK096418 BC034694 AAH34694 HQ447837 ADQ32321 U92314 AAC78498 U92315 AAC78499 XM_005259182 XP_005259239 NM_004605 NP_004596 NM_177973 NP_814444
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. {ECO:0000269|PubMed:12145317, ECO:0000269|PubMed:9799594}.
Subcellular Location Cytoplasm. Microsome. Nucleus. Note=Phosphorylation of Ser-348 is required for translocation to the nucleus.
Tissue Specificity Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung. {ECO:0000269|PubMed:9799594}.
Top Pathways Steroid hormone biosynthesis

Human SULT2B1 full length protein - ab93936 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of ab93936 (3µg)

Human SULT2B1 full length protein - ab117696 from Abcam

Category Protein
Source E. coli
Species Human

Human SULT2B1 protein fragment - ab173038 from Abcam

Category Protein
Source E. coli
Species Human

SULT2B1 Antibody Blocking Peptide - LS-E18411 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SULT2B1 Antibody Blocking Peptide - LS-E17585 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SULT2B1 Antibody Blocking Peptide - LS-E17584 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SULT2B1 Antibody Blocking Peptide - LS-E7006 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Cytosolic Sulfotransferase 2B1/SULT2B1 Recombinant Protein - H00006820-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Cytosolic Sulfotransferase 2B1/SULT2B1 Partial Recombinant Protein - H00006820-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human Cytosolic Sulfotransferase 2B1/SULT2B1 Protein - NBP1-41135 from Novus Biologicals

Category Protein
Prices $269.00
Sizes 100 µg
Source E. coli
Species Human
SDS-Page: SULT2B1 Protein [NBP1-41135] - SULT2B1, 41.3 kDa (365aa), confirmed by MALDI-TOF with a purity of 85% by SDS - PAGE

SULT2B1ab-Antibody-N-term-Blocking-peptide - BP2604a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human SULT2B1, CF - 6174-ST-020 from R&D Systems

Category Protein
Source E. coli-derived, Met1-Glu311, with a C-terminal 6-His tag

SULT2B1 Protein (OPPA02374) - OPPA02374 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 5 µg
Source E. Coli

Human SULT2B1 protein - orb163437 from Biorbyt

Category Protein
Prices $306.00, $400.00, $1,904.00, $2,695.00
Sizes 10 μg, 50 μg, 500 μg, 1 mg
Species Human

Human SULT2B1 protein - orb90273 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 25 μg
Source E.coli
Species Human

Human SULT2B1 His tag protein - orb83863 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 20 μg, 50 μg
Source E. coli
Species Human
SDS-PAGE analysis of human SULT2B1 His tag protein

SULT2B1 Blocking Peptide - 33R-6902 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SULT2B1 Blocking Peptide - 33R-10242 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SULT2B1 Blocking Peptide - 33R-5757 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SULT2B1 protein - 30R-1510 from Fitzgerald

Category Protein
Prices $220.00
Sizes 100 µg
Source E.coli

SULT2B1 (1-365) - AR09409PU-L from Acris Antibodies

Category Protein
Prices $695.00
Sizes 500 µg
Source E. coli
Species Human
SULT2B1

SULT2B1 (1-365) - AR09409PU-N from Acris Antibodies

Category Protein
Prices $305.00
Sizes 100 µg
Source E. coli
Species Human
SULT2B1

SULT2B1 - H00006820-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

SULT2B1 - H00006820-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

SULT2B1 - H00006820-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human
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