SULT2B1

Gene Symbol SULT2B1
Entrez Gene 6820
Alt Symbol HSST2
Species Human
Gene Type protein-coding
Description sulfotransferase family, cytosolic, 2B, member 1
Other Description ST2B1|alcohol sulfotransferase|hydroxysteroid sulfotransferase 2|sulfotransferase 2B1|sulfotransferase family cytosolic 2B member 1
Swissprots O00204 O75814 O00205
Accessions AAC78553 AAC78554 EAW52354 EAW52355 O00204 AK096418 BC034694 AAH34694 HQ447837 ADQ32321 U92314 AAC78498 U92315 AAC78499 XM_005259182 XP_005259239 NM_004605 NP_004596 NM_177973 NP_814444
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. {ECO:0000269|PubMed:12145317, ECO:0000269|PubMed:9799594}.
Subcellular Location Cytoplasm. Microsome. Nucleus. Note=Phosphorylation of Ser-348 is required for translocation to the nucleus.
Tissue Specificity Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung. {ECO:0000269|PubMed:9799594}.
Top Pathways Steroid hormone biosynthesis

SULT2B1 CRISPR/Cas9 KO Plasmid (h) - sc-404529 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SULT2B1 HDR Plasmid (h) - sc-404529-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SULT2B1 Double Nickase Plasmid (h) - sc-404529-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SULT2B1 Double Nickase Plasmid (h2) - sc-404529-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SULT2B1 CRISPR Activation Plasmid (h) - sc-404529-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SULT2B1 CRISPR Activation Plasmid (h2) - sc-404529-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SULT2B1 Lentiviral Activation Particles (h) - sc-404529-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SULT2B1 Lentiviral Activation Particles (h2) - sc-404529-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SULT2B1 siRNA (h) - sc-44399 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SULT2B1 shRNA Plasmid (h) - sc-44399-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SULT2B1 shRNA (h) Lentiviral Particles - sc-44399-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytosolic Sulfotransferase 2B1/SULT2B1 RNAi - H00006820-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU081291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20826 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20826 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SULT2B1 siRNA (Human) - CRH4664 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Cytosolic Sulfotransferase 2B1/SULT2B1 RNAi - H00006820-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SULT2B1 - MBS8231271 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SULT2B1 (NM_004605.2) - SHH420828 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SULT2B1(NM_177973.1) - SHL047640 from Creative biogene

Category siRNA
Species Reactivities Human

Human SULT2B1 siRNA - orb265166 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SULT2B1 shRNA Plasmid (Human) - CHH4664 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SULT2B1 miRNA 3'UTR clone - MiUTR1H-10057 from Creative biogene

Species Reactivities Human

SULT2B1 miRNA 3'UTR clone - MiUTR1H-10058 from Creative biogene

Species Reactivities Human
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