QKI

Gene Symbol	QKI
Entrez Gene	9444
Alt Symbol	Hqk, QK, QK1, QK3, hqkI
Species	Human
Gene Type	protein-coding
Description	QKI, KH domain containing, RNA binding
Other Description	RNA binding protein HQK|homolog of mouse quaking QKI (KH domain RNA binding protein)|protein quaking|quaking homolog, KH domain RNA binding
Swissprots	Q9P0X8 Q96KA3 Q96PU6 Q9P0X9 Q96EJ3 Q96PU7 Q969L9 Q9P0Y0 Q9P0X6 Q2I375 Q5MJQ1 Q96PU8 Q9P0X7 Q9P0Y1
Accessions	BAB69681 EAW47554 EAW47555 EAW47556 EAW47557 EAW47558 EAW47559 EAW47560 Q96PU8 AB067798 BAB69496 AB067799 BAB69497 AB067800 BAB69498 AB067801 BAB69499 AF142422 AAF63417 AF272349 AAL36980 AI146598 AJ420502 AK027309 BAB55032 AK055085 AK096701 AK295235 BAG58228 AK308784 AL050218 AW022136 AW131362 AY780788 AAV98358 BC008190 BC012222 AAH12222 BC019917 AAH19917 DQ323998 ABC88600 EU832828 ACE87839 GQ129383 ACT64517 HQ447847 ADQ32331 XM_011536258 XP_011534560 XM_011536259 XP_011534561 XM_011536260 XP_011534562 XM_011536261 XP_011534563 XR_245557 XR_942633 NM_001301085 NP_001288014 NM_006775 NP_006766 NM_206853 NP_996735 NM_206854 NP_996736 NM_206855 NP_996737
Function	RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Tissue Specificity	Expressed in the frontal cortex of brain. Down-regulated in the brain of schizophrenic patients. {ECO:0000269|PubMed:16342280}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

QKI (N-20) - sc-103851 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

QKI (U-24) - sc-130861 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Anti-QK1 antibody - ab77176 from Abcam Prices $376.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-QK1 antibody - ab104685 from Abcam Host Rabbit Clonality Polyclonal

Anti-QK1 antibody - ab78518 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-QK1 antibody [EPR7305(B)] - ab126791 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7305(B)

Anti-QK1 antibody [EPR7306] - ab126742 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7306

Anti-QK1 antibody [S147-6] - ab186245 from Abcam Prices $372.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S147-6

Anti-QKI Antibody (C-Terminus) - LS-C93518 from LifeSpan Bioscience Prices $635.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (aa50-100) - LS-C93517 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody - LS-C152865 from LifeSpan Bioscience Prices $385.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody - LS-C152866 from LifeSpan Bioscience Prices $385.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (aa1-341, clone S147-6) - LS-C209555 from LifeSpan Bioscience Prices $365.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S147-6

Anti-QKI Antibody (N-Terminus, AP) - LS-C281776 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (N-Terminus, Biotin) - LS-C281780 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (N-Terminus, APC) - LS-C281778 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (N-Terminus, FITC) - LS-C281781 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (N-Terminus, Azide-free, HRP) - LS-C281782 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (N-Terminus, PE) - LS-C281783 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (Internal, clone EPR7305(B)) - LS-C152399 from LifeSpan Bioscience Prices $475.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7305(B)

Anti-QKI Antibody (N-Terminus) - LS-C328424 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (aa52-101) - LS-C146556 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (aa6-17) - LS-C55349 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-QKI Antibody (aa50-100) - LS-C287105 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-QKI Antibody (aa1-30) IHC-plus™ - LS-B9016 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Search more