Gene Symbol |
CHAMP1
|
Entrez Gene |
283489
|
Alt Symbol |
C13orf8, CAMP, CHAMP, ZNF828
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chromosome alignment maintaining phosphoprotein 1
|
Other Description |
chromosome alignment-maintaining phosphoprotein 1|zinc finger protein 828
|
Swissprots |
Q6P181 Q9BST0 Q8NC88 B3KU06 Q96JM3
|
Accessions |
EAX09253 EAX09254 Q96JM3 AB058705 BAB47431 AK074894 BAC11273 AK096346 BAG53268 BC004820 AAH04820 BC019576 BC065237 AAH65237 BM663717 CN365659 DA289328 DB229502 EU446515 ABZ92044 NM_001164144 NP_001157616 NM_001164145 NP_001157617 NM_032436 NP_115812
|
Function |
Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore. {ECO:0000269|PubMed:21063390}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:21063390}. Chromosome {ECO:0000269|PubMed:21063390}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:21063390}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:21063390}.
|