Gene Symbol | CHAMP1 |
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Entrez Gene | 283489 |
Alt Symbol | C13orf8, CAMP, CHAMP, ZNF828 |
Species | Human |
Gene Type | protein-coding |
Description | chromosome alignment maintaining phosphoprotein 1 |
Other Description | chromosome alignment-maintaining phosphoprotein 1|zinc finger protein 828 |
Swissprots | Q6P181 Q9BST0 Q8NC88 B3KU06 Q96JM3 |
Accessions | EAX09253 EAX09254 Q96JM3 AB058705 BAB47431 AK074894 BAC11273 AK096346 BAG53268 BC004820 AAH04820 BC019576 BC065237 AAH65237 BM663717 CN365659 DA289328 DB229502 EU446515 ABZ92044 NM_001164144 NP_001157616 NM_001164145 NP_001157617 NM_032436 NP_115812 |
Function | Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore. {ECO:0000269|PubMed:21063390}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:21063390}. Chromosome {ECO:0000269|PubMed:21063390}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:21063390}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:21063390}. |
ZNF828 CRISPR/Cas9 KO Plasmid (h) - sc-406379 from Santa Cruz Biotechnology
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ZNF828 HDR Plasmid (h) - sc-406379-HDR from Santa Cruz Biotechnology
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ZNF828 Double Nickase Plasmid (h) - sc-406379-NIC from Santa Cruz Biotechnology
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ZNF828 Double Nickase Plasmid (h2) - sc-406379-NIC-2 from Santa Cruz Biotechnology
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ZNF828 CRISPR Activation Plasmid (h) - sc-406379-ACT from Santa Cruz Biotechnology
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ZNF828 CRISPR Activation Plasmid (h2) - sc-406379-ACT-2 from Santa Cruz Biotechnology
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ZNF828 Lentiviral Activation Particles (h) - sc-406379-LAC from Santa Cruz Biotechnology
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ZNF828 Lentiviral Activation Particles (h2) - sc-406379-LAC-2 from Santa Cruz Biotechnology
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ZNF828 siRNA (h) - sc-105150 from Santa Cruz Biotechnology
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ZNF828 shRNA Plasmid (h) - sc-105150-SH from Santa Cruz Biotechnology
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ZNF828 shRNA (h) Lentiviral Particles - sc-105150-V from Santa Cruz Biotechnology
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ZNF828 RNAi - H00283489-R01 from Novus Biologicals
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CAMP/LL37/FALL39/Cathelicidin RNAi - H00000820-R01 from Novus Biologicals
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MISSION® esiRNA - EHU102001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23741 from Sigma-Aldrich
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CHAMP1 siRNA (Human) - CRJ6911 from Cohesion Biosciences
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CHAMP1 - MBS8221795 from MyBioSource
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shRNA set against Human ZNF828 (NM_032436.2) - SHH455448 from Creative biogene
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Human CHAMP1 siRNA - orb277412 from Biorbyt
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CHAMP1 shRNA Plasmid (Human) - CHJ6911 from Cohesion Biosciences
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CHAMP1 miRNA 3'UTR clone - MiUTR3H-14277 from Creative biogene
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CHAMP1 miRNA 3'UTR clone - MiUTR3H-14278 from Creative biogene
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CHAMP1 miRNA 3'UTR clone - MiUTR3H-14279 from Creative biogene
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