STXBP3

Gene Symbol STXBP3
Entrez Gene 6814
Alt Symbol MUNC18-3, MUNC18C, PSP, UNC-18C
Species Human
Gene Type protein-coding
Description syntaxin binding protein 3
Other Description platelet Sec1 protein|protein unc-18 homolog 3|protein unc-18 homolog C|syntaxin 4 binding protein|syntaxin-binding protein 3|unc18-3
Swissprots Q9UPD7 A8K5K7 O00186 Q86YJ3 Q53FW1 A8K269
Accessions EAW56330 EAW56331 EAW56332 O00186 AF032922 AAC69606 AK223170 BAD96890 AK290134 BAF82823 AK291322 BAF84011 AK312910 BAG35756 BC028028 BC038099 AAH38099 BC047764 AAH47764 CN409056 D63506 BAA19482 NM_007269 NP_009200
Function Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:10194441}. Cell membrane {ECO:0000269|PubMed:10194441}. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated.
Tissue Specificity Megakaryocytes and platelets.

Unc18-3 (C-15) - sc-14567 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Unc18-3 (E-15) - sc-14566 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Unc18-3 (E-15): sc-14566. Western blot analysis of Unc18-3 expression in non-transfected: sc-117752 (A) and human Unc18-3 transfected: sc-116071 (B) 293T whole cell lysates.

Unc18-3 (H-7) - sc-373813 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Unc18-3 (H-7): sc-373813. Western blot analysis of Unc18-3 expression in non-transfected 293T: sc-117752 (A), human Unc18-3 transfected 293T: sc-116071 (B) and MEG-01 (C) whole cell lysates.

Unc18-3 (H-96) - sc-28930 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Unc18-3 (H-96): sc-28930. Western blot analysis of Unc18-3 expression in non-transfected: sc-117752 (A) and human Unc18-3 transfected: sc-116071 (B) 293T whole cell lysates.

Anti-Munc18c antibody - ab194954 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
All lanes : Anti-Munc18c antibody (ab194954) at 1 µg/mlLane 1 : Mouse spleen lysate (in RIPA buffer)Lane 2 : Rat spleen lysate (in RIPA buffer)Lysates/proteins at 35 µg per lane.developed using the ECL technique

Anti-Munc18c antibody - ab112934 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Munc18c antibody (ab112934) at 1/100 dilution + SK-BR-3 cell line lysates at 35 µg

Anti-Munc18c antibody - ab194964 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Munc18c antibody (ab194964) at 0.1 µg/ml + human platelet lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-Munc18c antibody [EPR12446] - ab182004 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12446
Flow cytometric analysis of 2% paraformaldehyde-fixed K562 cells labeling Munc18c with ab182004 at 1/300 dilution (red) compared to a Rabbit monoclonal IgG Isotype control (green), followed by Goat anti rabbit IgG (FITC) secondary antibody at 1/150 dilution.

Anti-Munc18c antibody [EPR12447] - ab175238 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12447
Immunofluorescent analysis of K562 cells labeling Munc18c with ab175238 at 1/100 (red) and DAPI staining (blue).

Anti-STXBP3 Antibody (aa144-171) - LS-C325485 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STXBP3 Antibody (aa463-512) - LS-C151737 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
STXBP3 antibody Western Blot of NCI-H226.

Anti-STXBP3 Antibody (aa144-171) - LS-C161599 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
STXBP3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-STXBP3 Antibody (aa144-171, PE) - LS-C270654 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STXBP3 Antibody (aa144-171, AP) - LS-C270649 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STXBP3 Antibody (aa144-171, APC) - LS-C270650 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STXBP3 Antibody (aa144-171, Biotin) - LS-C270651 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STXBP3 Antibody (aa144-171, FITC) - LS-C270652 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STXBP3 Antibody (aa144-171, Azide-free, HRP) - LS-C270653 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Syntaxin-BP3/Munc18c Antibody - NBP1-80636 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Syntaxin-BP3/Munc18c Antibody [Unconjugated] - AF5659 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Syntaxin-BP3/Munc18c Antibody - H00006814-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Syntaxin-BP3/Munc18c Antibody [H00006814-B01P] - Analysis of STXBP3 expression in transfected 293T cell line by STXBP3 polyclonal antibody.  Lane 1: STXBP3 transfected lysate(65.12 KDa). Lane 2: Non-transfected lysate.

Unc18-3 Polyclonal Antibody - bs-6462R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-STXBP3 antibody produced in rabbit - HPA027225 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-STXBP3: <B>Cat. No. HPA027225</B>: Immunohistochemical staining of human pancreas shows distinct positivity in the luminal membranes of intercalated ducts.

Anti-Munc-18-3 antibody produced in rabbit - M7695 from Sigma-Aldrich

Prices $70.70, $353.50
Sizes 25 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Mouse brain (S1 fraction) extract was separated on SDS-PAGE and blotted with Anti-Munc-18-3 (<B>Cat. No. M7695</B>). The antibody was developed with Goat Anti-Rabbit IgG, Peroxidase conjugate (<B>Cat. No. A0545</B>) and chemiluminescent substrate. Antibody dilution 1:1,000<BR/><B>Lanes</B><BR/>1,2: Mouse brain (S1 fraction)<BR/>2: Inhibition with Munc-18-3 (mouse, 578-592) peptide (10 μg/mL)

Anti-STXBP3 antibody produced in mouse - SAB1406498 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-STXBP3: <B>Cat. No. SAB1406498</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~65.1 kDa using STXBP3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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