Gene Symbol | CLEC4D |
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Entrez Gene | 338339 |
Alt Symbol | CLEC-6, CLEC6, CLECSF8, MCL, MPCL |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 4, member D |
Other Description | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8|C-type lectin domain family 4 member D|C-type lectin receptor|C-type lectin superfamily member 8|C-type lectin-like receptor 6|macrophage C-type lectin |
Swissprots | Q8WXI8 Q8N5J5 |
Accessions | EAW88619 Q8WXI8 AF411850 AAL37713 AK314071 AY115592 AAM75389 AY297446 AAQ63173 AY486482 AAS59161 AY486483 AAS59162 BC032313 AAH32313 BI909298 DQ894429 ABM85355 XM_011520632 XP_011518934 XM_011520633 XP_011518935 NM_080387 NP_525126 |
Function | Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells. {ECO:0000269|PubMed:14971047}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed weakly in peripheral blood leukocytes, bone marrow and spleen. Expression is confined mostly in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-alpha and IFN-gamma. {ECO:0000269|PubMed:14971047}. |
CLEC-6 (A-15) - sc-49418 from Santa Cruz Biotechnology
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CLEC-6 (C-20) - sc-49419 from Santa Cruz Biotechnology
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CLEC-6 (H-87) - sc-134742 from Santa Cruz Biotechnology
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CLEC-6 (M-77) - sc-134743 from Santa Cruz Biotechnology
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Anti-CLEC4D antibody - ab175021 from Abcam
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Anti-CLEC4D antibody - ab173173 from Abcam
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Anti-CLEC4D antibody - ab69396 from Abcam
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Anti-CLEC4D antibody - ab130931 from Abcam
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Anti-CLEC4D antibody - ab192527 from Abcam
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Anti-CLEC4D / MCL Antibody - LS-C332220 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa52-215) - LS-C35948 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa52-215, APC) - LS-C128189 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa52-215, PE) - LS-C128190 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa125-153, APC) - LS-C233935 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa125-153, AP) - LS-C233936 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa125-153, Biotin) - LS-C233937 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa134-183) - LS-C151486 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa125-153, PE) - LS-C233941 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa125-153, FITC) - LS-C233938 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa125-153, Azide-free, HRP) - LS-C249694 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa125-153) - LS-C329389 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody - LS-C306988 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody - LS-C341475 from LifeSpan Bioscience
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Anti-CLEC4D / MCL Antibody (aa125-153) - LS-C159366 from LifeSpan Bioscience
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CLEC4D/CLECSF8 Antibody (413512) - MAB2806 from Novus Biologicals
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