STRADB

Gene Symbol STRADB
Entrez Gene 55437
Alt Symbol ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK, PRO1038
Species Human
Gene Type protein-coding
Description STE20-related kinase adaptor beta
Other Description ILP-interacting protein ILPIPA|STE20-related kinase adapter protein beta|STRAD beta|amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein|pseudokinase ALS2CR2
Swissprots Q9C0K7 Q9P1L0 Q5BKY7
Accessions AAY14692 CAE92102 EAW70273 EAW70274 EAW70275 EAW70276 Q9C0K7 AB038950 BAB32500 AF116618 AAF71042 AK024720 AK027637 BAB55254 AK290457 BAF83146 AY093697 AAM19143 BC008302 AAH08302 BC090871 AAH90871 BG110753 DQ893688 ABM84614 DQ893689 ABM84615 DQ896519 ABM87518 DQ896865 ABM87864 EU176785 ABW03586 EU176786 ABW03587 W74591 XM_005246669 XP_005246726 NM_001206864 NP_001193793 NM_018571 NP_061041
Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14517248}. Cytoplasm {ECO:0000269|PubMed:14517248}.
Tissue Specificity Highly expressed in heart, skeletal muscle, testis, liver and colon. {ECO:0000269|PubMed:11161814, ECO:0000269|PubMed:12048196}.
Top Pathways AMPK signaling pathway

ILPIP (C-12) - sc-376694 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ILPIP (F-11): sc-376694. Western blot analysis of ILPIP expression in human heart tissue extract.

ILPIP (F-10) - sc-390494 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ILPIP (F-10): sc-390494. Western blot analysis of ILPIP expression in human heart tissue extract.

ILPIP (H-80) - sc-134585 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ILPIP (N-20) - sc-48549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ILPIP (N-20): sc-48549. Western blot analysis of ILPIP expression in NCI-H460 whole cell lysate.

ILPIP (N-12) - sc-48548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ILPIP (C-15) - sc-48546 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ILPIP (C-15): sc-48546. Western blot analysis of ILPIP expression in A-10 whole cell lysate.

Anti-ALS2CR2 antibody - ab17205 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-ALS2CR2 antibody (ab17205) at 0.5 µg/mlLane 2 : Anti-ALS2CR2 antibody (ab17205) at 1 µg/mlLane 3 : Anti-ALS2CR2 antibody (ab17205) at 2 µg/mlLane 1 : Human heart lysateLane 2 : Human heart lysateLane 3 : Human heart lysateObserved band size : 34 kDa (why is the actual band size different from the predicted?)

Anti-ALS2CR2 antibody - ab62340 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-ALS2CR2 antibody (ab62340) at 1 µg/mlLane 2 : Anti-ALS2CR2 antibody (ab62340) at 2 µg/mlLane 1 : human brain lysateLane 2 : human brain lysate

Anti-ALS2CR2 antibody - ab117421 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab117421, at 3.75 ug/ml, staining ALS2CR2 in Formalin-fixed, Paraffin-embedded Human Heart tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-ALS2CR2 antibody - ab4122 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ALS2CR2 antibody - ab194417 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-ALS2CR2 antibody (ab194417) at 1/500 dilution + HeLa cell lysate at 50 µg

Anti-ALS2CR2 antibody - C-terminal - ab154703 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ALS2CR2 antibody - C-terminal (ab154703) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-ALS2CR2 antibody - N-terminal - ab199876 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-ALS2CR2 antibody - N-terminal (ab199876) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : Mouse thymus total cell extract

Anti-STRADB / ALS2CR2 Antibody (C-Terminus) IHC-plus™ - LS-B2747 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-STRADB antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2747 concentration 75 ug/ml.

Anti-STRADB / ALS2CR2 Antibody (aa399-418) - LS-C2824 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (Internal) - LS-C24645 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (C-Terminus) - LS-C24646 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (aa399-418) - LS-C40717 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody - LS-C83394 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (C-Terminus) - LS-C121114 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (aa8-25) - LS-C148958 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (aa389-418, APC) - LS-C241384 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (aa389-418, Biotin) - LS-C241386 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (aa389-418, FITC) - LS-C241387 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADB / ALS2CR2 Antibody (aa389-418, PE) - LS-C241391 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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