STRADB

Gene Symbol STRADB
Entrez Gene 55437
Alt Symbol ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK, PRO1038
Species Human
Gene Type protein-coding
Description STE20-related kinase adaptor beta
Other Description ILP-interacting protein ILPIPA|STE20-related kinase adapter protein beta|STRAD beta|amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein|pseudokinase ALS2CR2
Swissprots Q9C0K7 Q9P1L0 Q5BKY7
Accessions AAY14692 CAE92102 EAW70273 EAW70274 EAW70275 EAW70276 Q9C0K7 AB038950 BAB32500 AF116618 AAF71042 AK024720 AK027637 BAB55254 AK290457 BAF83146 AY093697 AAM19143 BC008302 AAH08302 BC090871 AAH90871 BG110753 DQ893688 ABM84614 DQ893689 ABM84615 DQ896519 ABM87518 DQ896865 ABM87864 EU176785 ABW03586 EU176786 ABW03587 W74591 XM_005246669 XP_005246726 NM_001206864 NP_001193793 NM_018571 NP_061041
Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14517248}. Cytoplasm {ECO:0000269|PubMed:14517248}.
Tissue Specificity Highly expressed in heart, skeletal muscle, testis, liver and colon. {ECO:0000269|PubMed:11161814, ECO:0000269|PubMed:12048196}.
Top Pathways AMPK signaling pathway

ILPIP CRISPR/Cas9 KO Plasmid (h) - sc-416879 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ILPIP HDR Plasmid (h) - sc-416879-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ILPIP Double Nickase Plasmid (h) - sc-416879-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ILPIP Double Nickase Plasmid (h2) - sc-416879-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ILPIP CRISPR Activation Plasmid (h) - sc-416879-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ILPIP CRISPR Activation Plasmid (h2) - sc-416879-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ILPIP Lentiviral Activation Particles (h) - sc-416879-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ILPIP Lentiviral Activation Particles (h2) - sc-416879-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ILPIP siRNA (h) - sc-60842 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ILPIP shRNA Plasmid (h) - sc-60842-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ILPIP shRNA (h) Lentiviral Particles - sc-60842-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALS2CR2 RNAi - H00055437-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU108721 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK2211 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2212 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2210 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN20765 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20765 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06288 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06288

STRADB siRNA (Human) - CRJ0703 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STRADB - MBS8227713 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human STRADB (NM_018571.5) - SHH420116 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ALS2CR2(NM_018571.5) - SHG054943 from Creative biogene

Category siRNA
Species Reactivities Human

Human STRADB siRNA - orb271204 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STRADB shRNA Plasmid (Human) - CHJ0703 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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