SAMD8

Gene Symbol SAMD8
Entrez Gene 142891
Alt Symbol HEL-177, SMSr
Species Human
Gene Type protein-coding
Description sterile alpha motif domain containing 8
Other Description CPE synthase|SAM domain-containing protein 8|ceramide phosphoethanolamine synthase|epididymis luminal protein 177|sphingomyelin synthase related|sphingomyelin synthase-related protein 1|sterile alpha motif domain-containing protein 8
Swissprots Q66K52 Q5JSC5 Q5JSC8 Q96LT4
Accessions EAW54565 EAW54566 EAW54567 EAW54568 Q96LT4 AK057811 BAB71586 BC080593 AAH80593 BC140219 AAI40220 BC146556 AAI46557 EU668332 ACF94485 XM_005269541 XP_005269598 XM_011539311 XP_011537613 XM_011539312 XP_011537614 XM_011539313 XP_011537615 NM_001174156 NP_001167627 NM_144660 NP_653261
Function Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway. {ECO:0000269|PubMed:19506037}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:19506037}; Multi-pass membrane protein {ECO:0000269|PubMed:19506037}.

SAMD8 CRISPR/Cas9 KO Plasmid (h) - sc-416890 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAMD8 HDR Plasmid (h) - sc-416890-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAMD8 Double Nickase Plasmid (h) - sc-416890-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAMD8 Double Nickase Plasmid (h2) - sc-416890-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAMD8 CRISPR Activation Plasmid (h) - sc-416890-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAMD8 CRISPR Activation Plasmid (h2) - sc-416890-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAMD8 Lentiviral Activation Particles (h) - sc-416890-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAMD8 Lentiviral Activation Particles (h2) - sc-416890-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAMD8 siRNA (h) - sc-90448 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SAMD8 shRNA Plasmid (h) - sc-90448-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SAMD8 shRNA (h) Lentiviral Particles - sc-90448-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU076061 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18836 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18836 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04469 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04469

SAMD8 siRNA (Human) - CRJ5359 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SAMD8 - MBS8207406 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Samd8 (NM_144660.2) - SHH401696 from Creative biogene

Category siRNA
Species Reactivities Human

Human SAMD8 siRNA - orb275860 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SAMD8 shRNA Plasmid (Human) - CHJ5359 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SAMD8 miRNA 3'UTR clone - MiUTR4H-TG07784 from Creative biogene

Species Reactivities Human
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