LETMD1

Gene Symbol LETMD1
Entrez Gene 25875
Alt Symbol 1110019O13Rik, HCCR-1, HCCR-2, HCCR1, HCRR-2
Species Human
Gene Type protein-coding
Description LETM1 domain containing 1
Other Description LETM1 domain-containing protein 1|cervical cancer 1 proto-oncogene protein p40|cervical cancer proto-oncogene 2 protein|regulator of TP53
Swissprots Q9Y3X3 Q6X2E4 B3KXK7 Q96PK7 Q6X2E5 A6NER7 Q6P1Q0 Q9BY59 Q7L690 Q7L2G9 Q8WXW6
Accessions EAW58166 EAW58167 EAW58168 EAW58169 EAW58170 EAW58171 EAW58172 Q6P1Q0 AF195651 AAK34885 AF315598 AAL26878 AF329277 AAL56993 AI313513 AK000639 AK057866 AK123080 AK126372 AK127540 BAG54519 AK225836 AK301898 BAH13580 AK301955 BAH13594 AK304707 BAH14243 AK315119 BAG37574 AL050286 CAB43387 AL079293 AY259835 AAP85624 AY259836 AAP85625 BC000395 AAH00395 BC019274 AAH19274 BC064943 AAH64943 BM549678 BM998643 BX343550 BX376670 DA682074 DC357852 HQ448111 ADQ32592 XM_006719335 XP_006719398 XM_006719336 XP_006719399 XM_006719338 XP_006719401 XM_006719339 XP_006719402 XM_006719340 XP_006719403 XM_011538161 XP_011536463 XM_011538162 XP_011536464 XM_011538163 XP_011536465 XM_011538164 XP_011536466 XM_011538165 XP_011536467 XM_011538166 XP_011536468 XM_011538167 XP_011536469 XR_944516 NM_001243689 NP_001230618 NM_001300765 NP_001287694 NM_015416 NP_056231 NR_045017 NR_045018 NR_045019 NR_045020 NM_001024668 NM_001024669 NM_001024670 NM_001024671
Function Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. {ECO:0000269|PubMed:12879013}.
Subcellular Location Mitochondrion outer membrane {ECO:0000269|PubMed:17943721, ECO:0000269|PubMed:18045496}; Single-pass membrane protein {ECO:0000269|PubMed:17943721, ECO:0000269|PubMed:18045496}.
Tissue Specificity Kidney, liver, skeletal muscle, heart and brain. Overexpressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix. {ECO:0000269|PubMed:12879013}.

HCCR-1 (Q-15) - sc-161697 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HCCR-1 (Q-15): sc-161697. Western blot analysis of HCCR-1 expression in SKBR-3 (A) and T-47D (B) whole cell lysates.

HCCR-1 (H-100) - sc-366177 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HCCR-1 (H-100): sc-366177. Western blot analysis of HCCR-1 expression in K-562 (A) and A549 (B) whole cell lysates.

HCCR-1 (G-14) - sc-161696 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HCCR-1 (G-14): sc-161696. Western blot analysis of HCCR-1 expression in mouse skeletal muscle tissue extract.

Anti-LETMD1 antibody - ab201215 from Abcam

Prices $359.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin-embedded Human kidney carcinoma tissue sections labeling LETMD1 with ab201215 at a 1/100 dilution.

Anti-LETMD1 antibody - ab67093 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-LETMD1 antibody (ab67093) at 1/500 dilutionLane 1 : LETMD1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg/ml per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-LETMD1 / HCCR1 Antibody - LS-C308746 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-LETMD1 / HCCR1 Antibody - LS-C192962 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of PANC1 cell lines, using LETMD1 antibody.

Anti-LETMD1 / HCCR1 Antibody (aa271-320) - LS-C116277 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
LETMD1 antibody LS-C116277 Western blot of PANC1 cell lysate.

Anti-LETMD1 / HCCR1 Antibody - LS-C335200 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human kidney cancer using LETMD1 antibody at dilution of 1:200 (x400 lens).

LETMD1 Antibody - NBP1-59843 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LETMD1 Antibody [NBP1-59843] - PANC1 cell lysate, concentration 0.2-1 ug/ml.

LETMD1 Antibody - H00025875-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: LETMD1 Antibody [H00025875-B01P] - Analysis of LETMD1 expression in transfected 293T cell line by LETMD1 polyclonal antibody. Lane 1: LETMD1 transfected lysate(39.6 KDa). Lane 2: Non-transfected lysate.

LETMD1 Polyclonal Antibody - bs-5937R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LETMD1 antibody produced in mouse - SAB1407257 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LETMD1: <B>Cat. No. SAB1407257</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~39.6 kDa using LETMD1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-LETMD1 antibody produced in rabbit - SAB4300728 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LETMD1 antibody - middle region (ARP44736_P050) - ARP44736_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BRI3B antibody - GTX87070 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-BRI3B antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX87070

LETMD1 antibody - GTX54331 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-LETMD1 antibody used in Western blot. GTX54331

LETMD1 antibody, Internal - GTX46643 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

Rabbit Anti Human LETMD1 (OACA02339) - OACA02339 from Aviva Systems Biology

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

LETMD1 antibody - 70R-35423 from Fitzgerald

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

LETMD1 antibody - 70R-6755 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

BRI3BP antibody - 70R-7252 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti -LETMD1 (HCCR1, HCCR-1, HCCR-2, HCRR-2, 1110019O13Rik) - 223894 from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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