| Gene Symbol |
NPNT
|
| Entrez Gene |
255743
|
| Alt Symbol |
EGFL6L, POEM
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nephronectin
|
| Other Description |
preosteoblast EGF-like repeat protein with MAM domain
|
| Swissprots |
D6RCA1 B4E2H7 A8K1W4 E9PE64 E9PCK8 B4DIT4 E9PF04 B4E3H2 A6NFT9 E9PCQ1 Q6UXI9 B4DYK3
|
| Accessions |
EAX06194 EAX06195 EAX06196 EAX06197 Q6UXI9 AK172856 AK290029 BAF82718 AK295772 BAG58596 AK302477 BAG63765 AK304279 BAG65139 AK304721 BAG65484 AL832465 AW607534 AY358336 AAQ88702 BC131587 BC166654 AAI66654 BM970581 CD109759 XM_005262888 XP_005262945 XM_005262890 XP_005262947 XM_011531820 XP_011530122 XM_011531821 XP_011530123 XM_011531822 XP_011530124 XM_011531823 XP_011530125 XM_011531824 XP_011530126 XM_011531825 XP_011530127 XM_011531826 XP_011530128 NM_198278 NM_001033047 NP_001028219 NM_001184690 NP_001171619 NM_001184691 NP_001171620 NM_001184692 NP_001171621 NM_001184693 NP_001171622
|
| Function |
Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha- 8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Trapped on the cell surface or in the extracellular matrix. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in kidney and lung and to a lower extent in brain, pregnant uterus, placenta, thyroid gland and blood vessels. {ECO:0000269|PubMed:15754038}.
|