| Gene Symbol | NPNT |
|---|---|
| Entrez Gene | 255743 |
| Alt Symbol | EGFL6L, POEM |
| Species | Human |
| Gene Type | protein-coding |
| Description | nephronectin |
| Other Description | preosteoblast EGF-like repeat protein with MAM domain |
| Swissprots | D6RCA1 B4E2H7 A8K1W4 E9PE64 E9PCK8 B4DIT4 E9PF04 B4E3H2 A6NFT9 E9PCQ1 Q6UXI9 B4DYK3 |
| Accessions | EAX06194 EAX06195 EAX06196 EAX06197 Q6UXI9 AK172856 AK290029 BAF82718 AK295772 BAG58596 AK302477 BAG63765 AK304279 BAG65139 AK304721 BAG65484 AL832465 AW607534 AY358336 AAQ88702 BC131587 BC166654 AAI66654 BM970581 CD109759 XM_005262888 XP_005262945 XM_005262890 XP_005262947 XM_011531820 XP_011530122 XM_011531821 XP_011530123 XM_011531822 XP_011530124 XM_011531823 XP_011530125 XM_011531824 XP_011530126 XM_011531825 XP_011530127 XM_011531826 XP_011530128 NM_198278 NM_001033047 NP_001028219 NM_001184690 NP_001171619 NM_001184691 NP_001171620 NM_001184692 NP_001171621 NM_001184693 NP_001171622 |
| Function | Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha- 8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Trapped on the cell surface or in the extracellular matrix. {ECO:0000250}. |
| Tissue Specificity | Expressed in kidney and lung and to a lower extent in brain, pregnant uterus, placenta, thyroid gland and blood vessels. {ECO:0000269|PubMed:15754038}. |