SHOC2

Gene Symbol SHOC2
Entrez Gene 8036
Alt Symbol SIAA0862, SOC2, SUR8
Species Human
Gene Type protein-coding
Description soc-2 suppressor of clear homolog (C. elegans)
Other Description leucine-rich repeat protein SHOC-2
Swissprots Q5VZS8 Q5VZS9 B3KR23 A8K9W8 Q9UQ13 O76063
Accessions EAW49548 EAW49549 EAW49550 Q9UQ13 AB020669 BAA74885 AF054828 AAC25698 AF068920 AAC39856 AI202318 AK090820 BAG52235 AK292833 BAF85522 AK293271 BAG56800 BC044752 BC050445 AAH50445 BX649055 DB451165 XM_011540216 XP_011538518 NM_001269039 NP_001255968 NM_007373 NP_031399
Function Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. {ECO:0000269|PubMed:10783161, ECO:0000269|PubMed:16630891}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19684605}. Nucleus {ECO:0000269|PubMed:19684605}. Note=Translocates from cytoplasm to nucleus upon growth factor stimulation.

Sur-8 (E-18) - sc-79612 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Sur-8 (E-18): sc-79612. Western blot analysis of Sur-8 expression in non-transfected: sc-117752 (A) and mouse Sur-8 transfected: sc-123846 (B) 293T whole cell lysates.

Sur-8 (H-300) - sc-366896 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Sur-8 (H-300): sc-366896. Western blot analysis of Sur-8 expression in non-transfected 293T: sc-117752 (A), mouse Sur-8 transfected 293T: sc-123846 (B), Jurkat (C) and MCF7 (D) whole cell lysates.

Anti-Shoc2 / Sur8 antibody - ab106430 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Shoc2 / Sur8 antibody (ab106430) at 1 µg/mlLane 2 : Anti-Shoc2 / Sur8 antibody (ab106430) at 2 µg/mlLane 1 : Jurkat cell lysate Lane 2 : Jurkat cell lysate Lysates/proteins at 15 µg per lane.

Anti-Shoc2 / Sur8 antibody - ab100937 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Shoc2 / Sur8 antibody - N-terminal - ab181678 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (N-Terminus) - LS-C145141 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody - LS-C154775 from LifeSpan Bioscience

Prices $295.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (aa56-83, APC) - LS-C269376 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (aa56-83, AP) - LS-C269377 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (aa25-74) - LS-C151967 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SHOC2 antibody Western Blot of Jurkat cell lysate.

Anti-SHOC2 Antibody (aa56-83, Biotin) - LS-C269378 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (aa56-83, FITC) - LS-C269379 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (aa56-83, PE) - LS-C269380 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (aa55-83) - LS-C325102 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (aa56-83, Azide-free, HRP) - LS-C269382 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 Antibody (N-Terminus) - LS-C108459 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of SHOC2 in Jurkat cell lysate with SHOC2 antibody at (A) 1 and (B) 2 ug/ml. Below: Immunohistochemistry of SHOC2 in human spleen tissue with SHOC2 antibody at 5 ug/ml.

Anti-SHOC2 Antibody (aa76-125) - LS-C186770 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Fetal Kidney. SHOC2 antibody dilution 1.0 ug/ml.

Anti-SHOC2 Antibody (aa56-83) - LS-C158966 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SHOC2 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The SHOC2 antibody detected the SHOC2 protein (arrow).

SUR-8 Antibody - NBP1-87831 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SUR-8 Antibody - NBP1-77041 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SUR-8 Antibody [NBP1-77041] - Jurkat cell lysate with at (A) 1 and (B) 2 ug/mL.

SUR-8 Antibody - NBP1-48382 from Novus Biologicals

Prices $299.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

SHOC2 Polyclonal Antibody - bs-7934R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SHOC2 antibody produced in rabbit - HPA009164 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SHOC2: <B>Cat. No. HPA009164</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hippocampus tissue showing positive staining in neuronal cells.

Anti-SHOC2 antibody produced in rabbit - SAB3500051 from Sigma-Aldrich

Prices $316.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SHOC2: <B>Cat. No. SAB3500051</B>: SHOC2 in human spleen tissue with SHOC2 antibody at 5 μg/mL.

SHOC2 antibody - N-terminal region (ARP65381_P050) - ARP65381_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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