SHOC2

Gene Symbol SHOC2
Entrez Gene 8036
Alt Symbol SIAA0862, SOC2, SUR8
Species Human
Gene Type protein-coding
Description soc-2 suppressor of clear homolog (C. elegans)
Other Description leucine-rich repeat protein SHOC-2
Swissprots Q5VZS8 Q5VZS9 B3KR23 A8K9W8 Q9UQ13 O76063
Accessions EAW49548 EAW49549 EAW49550 Q9UQ13 AB020669 BAA74885 AF054828 AAC25698 AF068920 AAC39856 AI202318 AK090820 BAG52235 AK292833 BAF85522 AK293271 BAG56800 BC044752 BC050445 AAH50445 BX649055 DB451165 XM_011540216 XP_011538518 NM_001269039 NP_001255968 NM_007373 NP_031399
Function Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. {ECO:0000269|PubMed:10783161, ECO:0000269|PubMed:16630891}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19684605}. Nucleus {ECO:0000269|PubMed:19684605}. Note=Translocates from cytoplasm to nucleus upon growth factor stimulation.

Sur-8 CRISPR/Cas9 KO Plasmid (h) - sc-409478 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sur-8 HDR Plasmid (h) - sc-409478-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sur-8 Double Nickase Plasmid (h) - sc-409478-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sur-8 Double Nickase Plasmid (h2) - sc-409478-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sur-8 CRISPR Activation Plasmid (h) - sc-409478-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sur-8 CRISPR Activation Plasmid (h2) - sc-409478-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sur-8 Lentiviral Activation Particles (h) - sc-409478-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sur-8 Lentiviral Activation Particles (h2) - sc-409478-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sur-8 siRNA (h) - sc-76615 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sur-8 shRNA Plasmid (h) - sc-76615-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sur-8 shRNA (h) Lentiviral Particles - sc-76615-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU089311 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19310 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19310 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10450 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10450

SHOC2 siRNA (Human) - CRH5349 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SHOC2 - MBS8216200 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SHOC2 (NM_007373.3) - SHH407192 from Creative biogene

Category siRNA
Species Reactivities Human

Human SHOC2 siRNA - orb265851 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SHOC2 shRNA Plasmid (Human) - CHH5349 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SHOC2 miRNA 3'UTR clone - MiUTR3H-05309 from Creative biogene

Species Reactivities Human
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