TERF1

Gene Symbol	TERF1
Entrez Gene	7013
Alt Symbol	PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1
Species	Human
Gene Type	protein-coding
Description	telomeric repeat binding factor (NIMA-interacting) 1
Other Description	NIMA-interacting protein 2|TTAGGG repeat-binding factor 1|telomeric protein Pin2/TRF1|telomeric repeat-binding factor 1
Swissprots	Q93029 Q15553 Q8NHT6 A7XP29 P54274
Accessions	ABV02580 EAW86990 EAW86991 EAW86992 EAW86993 EAW86994 P54274 AF003001 AAB81137 AI218408 AK123410 AK292529 BAF85218 AY576778 AAT81150 BC014646 BC029378 AAH29378 BC071975 BF056993 CX788828 DA658766 DQ892573 ABM83499 DQ895789 ABM86715 U40705 AAB54036 U74382 AAB53363 X93511 CAA63768 XM_005251291 XP_005251348 XM_005251292 XP_005251349 XM_011517582 XP_011515884 NM_003218 NP_003209 NM_017489 NP_059523
Function	Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double- stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. {ECO:0000269|PubMed:16166375}.
Subcellular Location	Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, telomere. Note=Colocalizes with telomeric DNA in interphase and prophase cells. Telomeric localization decreases in metaphase, anaphase and telophase. Associates with the mitotic spindle.
Tissue Specificity	Highly expressed and ubiquitous. Isoform Pin2 predominates.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TRF1 full length protein - ab116406 from Abcam Category Protein Source E. coli Species Human

Human TRF1 peptide - ab97492 from Abcam Category Peptide

Human TRF1 peptide - ab22905 from Abcam Category Peptide Species Human

TRF1 / TERF1 Antibody Blocking Peptide - LS-E7078 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRF1 / TERF1 Antibody Blocking Peptide - LS-E25308 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TRF-1 Protein - H00007013-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TRF-1 Protein - H00007013-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TRF-1 Peptide - P1250 from Novus Biologicals Category Peptide Species Human

TRF-TERF1-Antibody-C-term-Blocking-peptide - BP2759b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TERF1-Antibody-N-term-Blocking-Peptide - BP2759a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TRF1 blocking peptide - GTX89932-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

TRBF1 peptide - orb73299 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

Human TERF1 Protein - abx069254 from Abbexa Category Protein Source E.coli Species Human

TERF1 (phospho-Ser219) Blocking Peptide - abx063338 from Abbexa Category Peptide Species Human, Mouse, Rat

TRF1 Peptide - AC21-0136-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TERF1 - H00007013-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TERF1 - H00007013-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TERF1 - H00007013-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TERF1 - H00007013-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TERF1 (1-419) - PRO-50044-0010 from Acris Antibodies Category Protein Prices $205.00 Sizes 10 µg Source E. coli Species Human

TERF1 (1-419) - PRO-50044-0025 from Acris Antibodies Category Protein Prices $235.00 Sizes 25 µg Source E. coli Species Human

TERF1 (1-419) - PRO-50044-0050 from Acris Antibodies Category Protein Prices $320.00 Sizes 50 µg Source E. coli Species Human

TERF1 (1-419) - PRO-50045-0010 from Acris Antibodies Category Protein Prices $205.00 Sizes 10 µg Source E. coli Species Human

TERF1 (1-419) - PRO-50045-0025 from Acris Antibodies Category Protein Prices $235.00 Sizes 25 µg Source E. coli Species Human

TERF1 (1-419) - PRO-50045-0050 from Acris Antibodies Category Protein Prices $320.00 Sizes 50 µg Source E. coli Species Human

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