Gene Symbol | CAV3 |
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Entrez Gene | 859 |
Alt Symbol | LGMD1C, LQT9, VIP-21, VIP21 |
Species | Human |
Gene Type | protein-coding |
Description | caveolin 3 |
Other Description | M-caveolin|caveolin-3 |
Swissprots | Q3T1A4 A8K777 P56539 |
Accessions | AAC39758 AAG02025 EAW63945 EAW63946 P56539 AA993189 AF036365 AAC39756 AF043101 AAC14931 AK291892 BAF84581 BC069368 AAH69368 BC102033 AAI02034 BC102036 AAI02037 BC102037 AAI02038 BF310794 BX114193 Y14747 CAA75042 NM_001234 NP_001225 NM_033337 NP_203123 |
Function | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed predominantly in muscle. {ECO:0000269|PubMed:9545514}. |
Top Pathways | Focal adhesion, Endocytosis, Bacterial invasion of epithelial cells, Proteoglycans in cancer |
Human Caveolin-3 full length protein - ab114264 from Abcam
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Human Caveolin-3 peptide - ab31791 from Abcam
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Human Caveolin-3 protein fragment - ab114265 from Abcam
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Mouse Caveolin-3 peptide - ab4930 from Abcam
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CAV3 / Caveolin 3 Antibody Blocking Peptide - LS-E10494 from LifeSpan Bioscience
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CAV3 / Caveolin 3 Antibody Blocking Peptide - LS-E8250 from LifeSpan Bioscience
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CAV3 / Caveolin 3 Antibody Blocking Peptide - LS-E27043 from LifeSpan Bioscience
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Recombinant Human Caveolin-3 Protein - H00000859-Q01 from Novus Biologicals
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Recombinant Human Caveolin-3 Protein - H00000859-P01 from Novus Biologicals
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CAV3-Antibody-N-term-Blocking-Peptide - BP6516a from Abgent, a WuXi AppTec company
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Caveolin 3 blocking peptide - GTX88437-PEP from GeneTex
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CAV3 Blocking Peptide - 33R-6224 from Fitzgerald
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Caveolin 3 Peptide - AC21-1866-P from Abcore
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Caveolin-3 - H00000859-P01-10 from Acris Antibodies
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Caveolin-3 - H00000859-P01-25 from Acris Antibodies
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Caveolin-3 - H00000859-Q01-10 from Acris Antibodies
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Caveolin-3 - H00000859-Q01-25 from Acris Antibodies
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Caveolin-3 Control Peptide - SP5144CP from Acris Antibodies
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Caveolin-3 Peptide - 46-992P from ProSci
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CAV3 fusion protein - ag17587 from Proteintech Group
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CAV3 fusion protein - ag17692 from Proteintech Group
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Recombinant Human caveolin 3 - CAV3-92H from Creative Biomart
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OVA Conjugated Caveolin 1 (CAV1) - CPA214Hu21 from Cloud-clone
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Recombinant Caveolin 1 (CAV1) - RPA214Hu01 from Cloud-clone
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Recombinant Human Caveolin-3(CAV3) - CSB-YP004573HU CSB-EP004573HU CSB-BP004573HU CSB-MP004573HU from Cusabio
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