SCN7A

Gene Symbol	SCN7A
Entrez Gene	6332
Alt Symbol	NaG, Nav2.1, Nav2.2, SCN6A
Species	Human
Gene Type	protein-coding
Description	sodium channel, voltage gated, type VII alpha subunit
Other Description	putative voltage-gated sodium channel subunit alpha Nax\|sodium channel protein cardiac and skeletal muscle subunit alpha\|sodium channel protein type 7 subunit alpha\|sodium channel protein type VII subunit alpha\|sodium channel, voltage-gated, type VI, alpha polypeptide\|sodium channel, voltage-gated, type VII, alpha subunit\|voltage-dependent sodium channel alpha subunit
Swissprots	Q01118
Accessions	EAX11312 EAX11313 Q01118 AK308450 BC062699 BC141864 CF129950 CK903677 M91556 AAA59899 S75992 AAD14203 XM_006712680 XP_006712743 XM_006712681 XP_006712744 XM_006712682 XP_006712745 XM_011511615 XP_011509917 NM_002976 NP_002967 NR_045628
Function	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Heart and uterus.
Top Pathways	Adrenergic signaling in cardiomyocytes

Na + CP type VIIα (C-19) - sc-130097 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	50 µg/0.5 ml
Host	Rabbit
Clonality	Polyclonal

Anti-SCN7A antibody - ab66499 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

IHC image of SCN7A staining in Human normal heart muscle formalin fixed paraffin embedded tissue section*, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab66499, 1/200 dilution, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.*Tissue obtained from the Human Research Tissue Bank, supported by the NIHR Cambridge Biomedical Research Centre

Anti-SCN7A Antibody (C-Terminus) - LS-C144777 from LifeSpan Bioscience

Prices	$365.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SCN7A Antibody - LS-C170816 from LifeSpan Bioscience

Prices	$365.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SCN7A Antibody (Lys810) - LS-C193163 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SCN7A Antibody (aa771-820) - LS-C120400 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence of A549 cells, using SCN7A Antibody. The picture on the right is treated with the synthesized peptide.

Anti-SCN7A Antibody (aa51-100) - LS-C201303 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Human Fetal Thymus. SCN7A antibody dilution 1.0 ug/ml.

SCN7A Antibody - NB100-81029 from Novus Biologicals

Prices	$299.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: SCN7A Antibody [NB100-81029] - Staining of sodium channel protein type 7 subunit alpha in human sperm cells.

SCN7A Antibody - NBP1-87075 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: SCN7A Antibody [NBP1-87075] - Staining of human lymph node shows strong nuclear positivity in reaction center cells.

SCN7A Polyclonal Antibody - bs-12127R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin embedded rat stomach labeled with Anti-SCN7A Polyclonal Antibody, Unconjugated (bs-12127R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

SCN7A Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12127R-A350 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12127R-A488 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12127R-A555 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12127R-A647 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, Cy3 Conjugated - bs-12127R-Cy3 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, Cy5 Conjugated - bs-12127R-Cy5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, Cy5.5 Conjugated - bs-12127R-Cy5.5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, Cy7 Conjugated - bs-12127R-Cy7 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, FITC Conjugated - bs-12127R-FITC from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, Biotin Conjugated - bs-12127R-Biotin from Bioss

Prices	$349.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Polyclonal Antibody, HRP Conjugated - bs-12127R-HRP from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SCN7A antibody produced in rabbit - SAB4502715 from Sigma-Aldrich

Prices	$335.50
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunofluorescence</B><BR/>Anti-SCN7A: <B>Cat. No. SAB4502715</B>: Immunofluorescence of A549 cells using Anti-SCN7A antibody. Cells on the left were treated with the Anti-SCN7A antibody. Cells on the right (negative control) were treated with both Anti-SCN7A antibody and the synthesized immunogen peptide.

Anti-SCN7A antibody produced in rabbit - HPA004879 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-SCN7A: <B>Cat. No. HPA004879</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing membranous and/or cytoplasmic staining of cells in tubules.

SCN7A Antibody - N-terminal region (ARP35113_P050) - ARP35113_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SCN7A Antibody (OAAF04304) - OAAF04304 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Search more