| Gene Symbol |
SCN7A
|
| Entrez Gene |
6332
|
| Alt Symbol |
NaG, Nav2.1, Nav2.2, SCN6A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sodium channel, voltage gated, type VII alpha subunit
|
| Other Description |
putative voltage-gated sodium channel subunit alpha Nax|sodium channel protein cardiac and skeletal muscle subunit alpha|sodium channel protein type 7 subunit alpha|sodium channel protein type VII subunit alpha|sodium channel, voltage-gated, type VI, alpha polypeptide|sodium channel, voltage-gated, type VII, alpha subunit|voltage-dependent sodium channel alpha subunit
|
| Swissprots |
Q01118
|
| Accessions |
EAX11312 EAX11313 Q01118 AK308450 BC062699 BC141864 CF129950 CK903677 M91556 AAA59899 S75992 AAD14203 XM_006712680 XP_006712743 XM_006712681 XP_006712744 XM_006712682 XP_006712745 XM_011511615 XP_011509917 NM_002976 NP_002967 NR_045628
|
| Function |
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Heart and uterus.
|
| Top Pathways |
Adrenergic signaling in cardiomyocytes
|