Gene Symbol | COMMD8 |
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Entrez Gene | 54951 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | COMM domain containing 8 |
Other Description | COMM domain-containing protein 8 |
Swissprots | Q9HC15 Q9NX08 Q8WUR4 |
Accessions | EAW93033 EAW93034 Q9NX08 AF182421 AAG14957 AK000509 BAA91216 AY542163 AAS22245 BC008371 AAH08371 BC015145 AAH15145 BC019826 AAH19826 HQ447967 ADQ32450 XM_006714019 XP_006714082 NM_017845 NP_060315 |
Function | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}. |
Tissue Specificity | Widely expressed with highest expression in thyroid. {ECO:0000269|PubMed:15799966}. |
COMMD8 CRISPR/Cas9 KO Plasmid (h) - sc-406868 from Santa Cruz Biotechnology
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COMMD8 HDR Plasmid (h) - sc-406868-HDR from Santa Cruz Biotechnology
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COMMD8 Double Nickase Plasmid (h) - sc-406868-NIC from Santa Cruz Biotechnology
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COMMD8 Double Nickase Plasmid (h2) - sc-406868-NIC-2 from Santa Cruz Biotechnology
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COMMD8 CRISPR Activation Plasmid (h) - sc-406868-ACT from Santa Cruz Biotechnology
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COMMD8 CRISPR Activation Plasmid (h2) - sc-406868-ACT-2 from Santa Cruz Biotechnology
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COMMD8 Lentiviral Activation Particles (h) - sc-406868-LAC from Santa Cruz Biotechnology
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COMMD8 Lentiviral Activation Particles (h2) - sc-406868-LAC-2 from Santa Cruz Biotechnology
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COMMD8 siRNA (h) - sc-89035 from Santa Cruz Biotechnology
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COMMD8 shRNA Plasmid (h) - sc-89035-SH from Santa Cruz Biotechnology
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COMMD8 shRNA (h) Lentiviral Particles - sc-89035-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU131631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6421 from Sigma-Aldrich
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COMMD8 siRNA (Human) - CRJ0351 from Cohesion Biosciences
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COMMD8 - MBS8221945 from MyBioSource
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shRNA set against Human COMMD8 (NM_017845.3) - SHH267653 from Creative biogene
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shRNA set against Human COMMD8(NM_017845.3) - SHG191941 from Creative biogene
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Human COMMD8 siRNA - orb270852 from Biorbyt
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COMMD8 shRNA Plasmid (Human) - CHJ0351 from Cohesion Biosciences
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COMMD8 miRNA 3'UTR clone - MiUTR1H-02343 from Creative biogene
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